伊朗东南部出现登革热感染疫情
Dengue Fever as an Emerging Infection in Southeast Iran.
机构信息
Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland.
出版信息
Am J Trop Med Hyg. 2018 May;98(5):1469-1471. doi: 10.4269/ajtmh.17-0634. Epub 2018 Mar 15.
Dengue fever (DF) is a mosquito-borne acute viral disease presenting with hemorrhagic manifestations in severe cases. Southeast Iran is in close proximity to Pakistan, an endemic country for DF. This cross-sectional study was conducted in the Sistan and Baluchestan province in the southeast of Iran to investigate possibility of DF (immunoglobulin M [IgM], immunoglobulin G [IgG], and nonstructural protein 1 [NS1] antigen tests) in 60 clinically suspected patients (April 2013 to August 2015). NS1 protein was detected in 5% ( = 3), at least one of the antibodies (IgM and/ or IgG) was detected in 11% ( = 7) of the samples. Five patients identified as of acutely infected. There was a simultaneous presence of NS1 protein and IgG or IgM antibodies in 4% ( = 2) of patients. Previous studies show establishment of potential vectors in this area. These evidences support the hypothesis that DF can be a health concern in Southeast Iran with potential future outbreaks.
登革热（DF）是一种由蚊子传播的急性病毒性疾病，在严重情况下会出现出血症状。伊朗东南部与巴基斯坦接壤，巴基斯坦是登革热的流行地区。本横断面研究在伊朗东南部的锡斯坦和俾路支省进行，目的是在 60 例临床疑似患者中（2013 年 4 月至 2015 年 8 月）调查登革热（免疫球蛋白 M [IgM]、免疫球蛋白 G [IgG]和非结构蛋白 1 [NS1]抗原检测）的可能性。在 5%（=3）的样本中检测到 NS1 蛋白，在 11%（=7）的样本中至少检测到一种抗体（IgM 和/或 IgG）。5 例患者被确定为急性感染。在 4%（=2）的患者中同时存在 NS1 蛋白和 IgG 或 IgM 抗体。先前的研究表明，该地区已经建立了潜在的媒介。这些证据支持了这样一种假设，即在伊朗东南部，登革热可能成为一个健康隐患，并有可能爆发未来的疫情。
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