伊朗献血者中西尼罗河病毒感染的频率
Frequency of West Nile Virus Infection in Iranian Blood Donors.
作者信息
Aghaie Afsaneh, Aaskov John, Chinikar Sadegh, Niedrig Matthias, Banazadeh Soudabeh, Mohammadpour Hashem Khorsand
机构信息
Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, P.O. Box 14665-1157, Tehran, Iran.
Queensland University of Technology, Brisbane, Australia.
出版信息
Indian J Hematol Blood Transfus. 2016 Sep;32(3):343-6. doi: 10.1007/s12288-015-0567-5. Epub 2015 Jul 30.
West Nile virus (WNV) can be transmitted by blood transfusions and organ transplants. This study was a retrospective study which was performed in Blood Transfusion Center to evaluate the WNV infection in blood donors in Iran. A total of 540 blood samples were taken from volunteer healthy donors who referred for blood donation to Chabahar Blood Center. The presence of WNV was studied by detecting immunoglobulin G (IgG) WNV by enzyme linked immune sorbent assay (ELISA). Demonstration of elevated WNV IgG confirmed by immunoflouorescence assay (IFA) Euroimmun kit. Out of the 540 samples 17.96 % (97 cases) were seropositive by ELISA and 1.48 % (8 cases) was seropositive by IFA. This means that 8.24 % of ELISA seropositive samples were confirmed by IFA. Special attention should be paid to criteria of donor selection, albeit positive results may be due to a previous infection in these donors.
西尼罗河病毒（WNV）可通过输血和器官移植传播。本研究是在输血中心进行的一项回顾性研究，旨在评估伊朗献血者中的WNV感染情况。总共从前往恰巴哈尔血液中心献血的健康志愿者中采集了540份血样。通过酶联免疫吸附测定（ELISA）检测免疫球蛋白G（IgG）WNV来研究WNV的存在情况。采用欧洲免疫（Euroimmun）试剂盒通过免疫荧光测定（IFA）确认WNV IgG升高。在540份样本中，ELISA检测显示17.96%（97例）血清呈阳性，IFA检测显示1.48%（8例）血清呈阳性。这意味着8.24%的ELISA血清阳性样本通过IFA得到了确认。尽管阳性结果可能是由于这些献血者先前感染所致，但仍应特别关注献血者选择标准。
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