Retinal ganglion cell neuroprotection by growth factors and exosomes: lessons from mesenchymal stem cells.
作者信息
Mead Ben, Tomarev Stanislav
机构信息
Section of Retinal Ganglion Cell Biology, Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
出版信息
Neural Regen Res. 2018 Feb;13(2):228-229. doi: 10.4103/1673-5374.226392.
Abstract
摘要
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Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Promote Neuroprotection in Rodent Models of Glaucoma.间质干细胞衍生的小细胞外囊泡促进青光眼啮齿动物模型的神经保护作用。
Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):702-714. doi: 10.1167/iovs.17-22855.
2
Neuroprotective Effects of Human Mesenchymal Stem Cells and Platelet-Derived Growth Factor on Human Retinal Ganglion Cells.人骨髓间充质干细胞和血小板衍生生长因子对人视网膜神经节细胞的神经保护作用。
Stem Cells. 2018 Jan;36(1):65-78. doi: 10.1002/stem.2722. Epub 2017 Oct 31.
3
Retinal Astrocytes and GABAergic Wide-Field Amacrine Cells Express PDGFRα: Connection to Retinal Ganglion Cell Neuroprotection by PDGF-AA.视网膜星形胶质细胞和γ-氨基丁酸能广域无长突细胞表达血小板衍生生长因子受体α：与血小板衍生生长因子-AA对视网膜神经节细胞的神经保护作用的联系。
Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4703-4711. doi: 10.1167/iovs.21783.
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Vision Loss after Intravitreal Injection of Autologous "Stem Cells" for AMD.玻璃体内注射自体“干细胞”治疗年龄相关性黄斑变性后的视力丧失
N Engl J Med. 2017 Mar 16;376(11):1047-1053. doi: 10.1056/NEJMoa1609583.
5
Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms.骨髓间充质干细胞衍生的外泌体通过 miRNA 依赖的机制促进视网膜神经节细胞的存活。
Stem Cells Transl Med. 2017 Apr;6(4):1273-1285. doi: 10.1002/sctm.16-0428. Epub 2017 Jan 26.
6
Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons.间充质基质细胞来源的外泌体促进皮质神经元轴突生长。
Mol Neurobiol. 2017 May;54(4):2659-2673. doi: 10.1007/s12035-016-9851-0. Epub 2016 Mar 19.
7
Platelet-Derived Growth Factor Preserves Retinal Synapses in a Rat Model of Ocular Hypertension.血小板衍生生长因子在高眼压大鼠模型中可保护视网膜突触。
Invest Ophthalmol Vis Sci. 2016 Mar;57(3):842-52. doi: 10.1167/iovs.15-17864.
8
Stem cell treatment of degenerative eye disease.干细胞治疗退行性眼病。
Stem Cell Res. 2015 May;14(3):243-57. doi: 10.1016/j.scr.2015.02.003. Epub 2015 Feb 24.
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Distribution of mesenchymal stem cells and effects on neuronal survival and axon regeneration after optic nerve crush and cell therapy.视神经挤压伤及细胞治疗后间充质干细胞的分布及其对神经元存活和轴突再生的影响
PLoS One. 2014 Oct 27;9(10):e110722. doi: 10.1371/journal.pone.0110722. eCollection 2014.
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Paracrine-mediated neuroprotection and neuritogenesis of axotomised retinal ganglion cells by human dental pulp stem cells: comparison with human bone marrow and adipose-derived mesenchymal stem cells.人牙髓干细胞旁分泌介导的视网膜神经节细胞轴突切断后的神经保护和神经突生成：与人类骨髓和脂肪来源的间充质干细胞的比较
PLoS One. 2014 Oct 7;9(10):e109305. doi: 10.1371/journal.pone.0109305. eCollection 2014.
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