Nathues H, Alarcon P, Rushton J, Jolie R, Fiebig K, Jimenez M, Geurts V, Nathues C
Clinic for Swine, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, Switzerland.
Veterinary Epidemiology, Economics and Public Health Group, Department of Production and Population Health, Royal Veterinary College of London, United Kingdom.
Prev Vet Med. 2018 Apr 1;152:89-102. doi: 10.1016/j.prevetmed.2018.02.005. Epub 2018 Feb 9.
PRRS is among the diseases with the highest economic impact in pig production worldwide. Different strategies have been developed and applied to combat PRRS at farm level. The broad variety of available intervention strategies makes it difficult to decide on the most cost-efficient strategy for a given farm situation, as it depends on many farm-individual factors like disease severity, prices or farm structure. Aim of this study was to create a simulation tool to estimate the cost-efficiency of different control strategies at individual farm level. Baseline is a model that estimates the costs of PRRS, based on changes in health and productivity, in a specific farm setting (e.g. farm type, herd size, type of batch farrowing). The model evaluates different intervention scenarios: depopulation/repopulation (D/R), close & roll-over (C&R), mass vaccination of sows (MS), mass vaccination of sows and vaccination of piglets (MS + piglets), improvements in internal biosecurity (BSM), and combinations of vaccinations with BSM. Data on improvement in health and productivity parameters for each intervention were obtained through literature review and from expert opinions. The economic efficiency of the different strategies was assessed over 5 years through investment appraisals: the resulting expected value (EV) indicated the most cost-effective strategy. Calculations were performed for 5 example scenarios with varying farm type (farrow-to-finish - breeding herd), disease severity (slightly - moderately - severely affected) and PRRSV detection (yes - no). The assumed herd size was 1000 sows with farm and price structure as commonly found in Germany. In a moderately affected (moderate deviations in health and productivity parameters from what could be expected in an average negative herd), unstable farrow-to-finish herd, the most cost-efficient strategies according to their median EV were C&R (€1'126'807) and MS + piglets (€ 1'114'649). In a slightly affected farrow-to-finish herd, no virus detected, the highest median EV was for MS + piglets (€ 721'745) and MS (€ 664'111). Results indicate that the expected benefits of interventions and the most efficient strategy depend on the individual farm situation, e.g. disease severity. The model provides new insights regarding the cost-efficiency of various PRRSV intervention strategies at farm level. It is a valuable tool for farmers and veterinarians to estimate expected economic consequences of an intervention for a specific farm setting and thus enables a better informed decision.
猪繁殖与呼吸综合征（PRRS）是全球养猪生产中经济影响最大的疾病之一。人们已制定并应用了不同策略在农场层面防控PRRS。现有干预策略种类繁多，这使得针对特定农场情况确定最具成本效益的策略变得困难，因为这取决于许多农场个体因素，如疾病严重程度、价格或农场结构。本研究的目的是创建一个模拟工具，以估计不同控制策略在个体农场层面的成本效益。基线是一个模型，它根据特定农场环境（如农场类型、猪群规模、批次分娩类型）中健康和生产力的变化来估计PRRS的成本。该模型评估不同的干预方案：清群/再引种（D/R）、封闭与周转（C&R）、母猪群体免疫（MS）、母猪群体免疫和仔猪免疫（MS + 仔猪）、内部生物安全改善（BSM）以及免疫与BSM的组合。通过文献综述和专家意见获得了每种干预措施在健康和生产力参数改善方面的数据。通过投资评估在5年内评估了不同策略的经济效率：所得预期值（EV）表明了最具成本效益的策略。针对5种不同农场类型（从分娩到育肥 - 繁殖猪群）、疾病严重程度（轻度 - 中度 - 重度感染）和PRRSV检测情况（是 - 否）的示例场景进行了计算。假设猪群规模为1000头母猪，农场和价格结构为德国常见情况。在一个受中度影响（健康和生产力参数与平均阴性猪群预期相比有中度偏差）、不稳定的从分娩到育肥猪群中，根据其EV中位数，最具成本效益的策略是C&R（1,126,807欧元）和MS + 仔猪（1,114,649欧元）。在一个受轻度影响、未检测到病毒的从分娩到育肥猪群中，EV中位数最高的是MS + 仔猪（721,745欧元）和MS（664,111欧元）。结果表明，干预措施的预期效益和最有效的策略取决于个体农场情况，如疾病严重程度。该模型为农场层面各种PRRSV干预策略成本效益提供了新的见解。它是农民和兽医估计特定农场环境中干预措施预期经济后果的宝贵工具，从而有助于做出更明智的决策。
