Zacharia Balaji, Subramaniam Dhiyaneswaran, Joy Jerin
1Department of Orthopedics, Government Medical College, Kakkathottam (H), Chevayoor (PO), Kozhikode, Kerala 673017 India.
Don Bosco Hospital, North Paravur, Ernakulam, Kerala India.
Indian J Surg Oncol. 2018 Mar;9(1):46-51. doi: 10.1007/s13193-017-0706-6. Epub 2017 Sep 28.
Metastasis is the commonest bone tumors. The commonest primary metastasis to the bone are the breast, lung, prostate, kidney, and thyroid. The bone is the third common site of metastatic disease, only the lung and the liver have higher metastatic rate than skeleton. We have no epidemiological studies conducted to evaluate the various aspects of skeletal metastasis like age, sex distribution, presentation, common sites of primary and associated secondary metastases, and investigation from Indian subcontinent. Here we are presenting the first epidemiological study of skeletal metastasis from our region. We have conducted a prospective descriptive study in the Departments of Orthopedics and Radiotherapy, Government Medical College, Kozhikode, during the period of 2007 to 2009. One hundred eleven patients were included in the study above the age of 30 years. Clinical examination and investigation were done on these patients. Skeletal metastasis commonly occurs in the fifth decade of life with modest male preponderance. In most of the cases, the primary site of malignancy was undetected at the time of presentation. Pain was the commonest presented complaint of the patient. The spine is the commonest site affected and the lung was the common site of primary metastasis. Most of the cases were detected by radiogram and confirmation was obtained by minimally invasive technique like FNAC or CNB.
骨转移是最常见的骨肿瘤。最常见的骨转移原发部位是乳腺、肺、前列腺、肾和甲状腺。骨是转移性疾病的第三常见部位，只有肺和肝的转移率高于骨骼。我们没有进行过流行病学研究来评估骨转移的各个方面，如年龄、性别分布、临床表现、原发及相关继发转移的常见部位，以及来自印度次大陆的调查情况。在此，我们展示了我们地区关于骨转移的首次流行病学研究。我们于2007年至2009年期间在科泽科德政府医学院的骨科和放疗科进行了一项前瞻性描述性研究。111名年龄在30岁以上的患者被纳入该研究。对这些患者进行了临床检查和调查。骨转移通常发生在生命的第五个十年，男性略占优势。在大多数病例中，就诊时恶性肿瘤的原发部位未被发现。疼痛是患者最常见的主诉。脊柱是最常受影响的部位，肺是原发转移的常见部位。大多数病例通过X线片检测到，并通过细针穿刺抽吸活检（FNAC）或粗针穿刺活检（CNB）等微创技术得以确诊。
