颈部肌张力障碍患者的感觉技巧：来自脑磁图的见解
Sensory Trick in a Patient with Cervical Dystonia: Insights from Magnetoencephalography.
作者信息
Mahajan Abhimanyu, Zillgitt Andrew, Bowyer Susan M, Sidiropoulos Christos
机构信息
Department of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, K-11, Detroit, MI 48202, USA.
Department of Neurology and Ophthalmology, Michigan State University, East Lansing, MI 48823, USA.
出版信息
Brain Sci. 2018 Mar 22;8(4):51. doi: 10.3390/brainsci8040051.
Abstract
BACKGROUND
The proposed mechanisms for the sensory trick include peripheral sensory feedback to aid in correcting abnormal posture or movement.
CASE REPORT
A 53-year-old woman with cervical dystonia underwent magnetoencephalography pre- and post-botulinum toxin injection and sensory trick, which was described as yawning. Study revealed connectivity between the left frontal and inferior frontal gyrus before yawning, which changed to the visual cortex and right middle frontal gyrus with yawning. Beta frequencies reduced and gamma frequencies increased after yawning.
DISCUSSION
The increase in gamma frequency bands may indicate increased GABAergic activity. Increase in connectivity in the right cerebellar region underscores the importance of cerebellum in pathogenesis of dystonia.
摘要
背景
感觉技巧的推测机制包括外周感觉反馈，以帮助纠正异常姿势或运动。
病例报告
一名53岁的颈肌张力障碍女性在肉毒杆菌毒素注射前后以及进行被描述为打哈欠的感觉技巧时接受了脑磁图检查。研究显示，打哈欠前左额叶和额下回之间存在连接，打哈欠时这种连接转变为视觉皮层和右额中回。打哈欠后β频率降低，γ频率增加。
讨论
γ频段频率增加可能表明GABA能活动增强。右小脑区域连接性的增加突出了小脑在肌张力障碍发病机制中的重要性。
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