Université de Carthage, Faculté des Sciences de Bizerte, Laboratoire de Biosurveillance de l'Environnement (LR01/ES14), 7021 Zarzouna, Tunisia; Université de Tunis-El-Manar, Faculté des Sciences de Tunis, Unité de Recherche de Biologie Intégrative et Écologie Évolutive et Fonctionnelle des Milieux Aquatiques (UR11/ES08), 2092 El Manar, Tunisia.
Institut National de l'Environnement Industriel et des Risques (INERIS), Unité d'Écotoxicologie In Vitro et In Vivo, f-60550 Verneuil-en-Halatte, France.
Mar Pollut Bull. 2018 Mar;128:248-258. doi: 10.1016/j.marpolbul.2018.01.028. Epub 2018 Jan 20.
The aim of this study was to appraise the response of a multi-marker approach in fish species, Gobius niger and Zosterisessor ophiocephalus, in a polluted lagoon (Bizerte lagoon: MB and ML sites) and in a reference site (Ghar-El-Melh lagoon entrance) by the analysis of physiological indexes, liver histopathology and some biochemical biomarkers. The results showed liver hypertrophy in fish collected from Bizerte lagoon as well as many non-specific lesions, unlike the reference site. All Bizerte lagoon sites had the same prevalence of histopathological lesions, but the mean intensity (MI) of parasites seemed to be more sensible as an indicator of pollution levels. Indeed, parasite MI was more important in MB site that has a higher pollution level. Also, biochemical biomarkers showed an induction in Bizerte lagoon sites with some differences within sites and species. The impact of the continuous release of pollution on the biomarker's response is discussed.
本研究旨在评估多标志物方法在受污染泻湖（比塞大泻湖：MB 和 ML 点）和参照点（盖尔梅勒泻湖入口）中的鱼类（黑鳍棘鲷和黄鳍棘鲷）中的反应，通过分析生理指标、肝组织病理学和一些生化生物标志物。结果表明，与参照点相比，来自比塞大泻湖的鱼类出现了肝脏肥大以及许多非特异性病变。比塞大泻湖所有地点的组织病理学病变的发生率相同，但寄生虫的平均强度（MI）似乎更能作为污染水平的指标。事实上，寄生虫 MI 在污染水平更高的 MB 点更为重要。此外，生化生物标志物在比塞大泻湖地点显示出诱导作用，各地点和物种之间存在差异。本文讨论了持续释放的污染物对生物标志物反应的影响。
