CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Perú.
Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Trop Med Int Health. 2018 May;23(5):533-540. doi: 10.1111/tmi.13052. Epub 2018 Apr 1.
High body mass index (BMI) and blood pressure (BP) are major contributors to the high burden of non-communicable diseases in adulthood. Individual high-risk and population approaches for prevention require newer strategies to target these risk factors and focusing on the family to introduce prevention initiatives appears as a promising scenario. Characterisation of the relationship between BMI and BP among the adult members of a given family merits evaluation. We conducted a secondary analysis of an implementation study in Tumbes, Peru, benefiting from data derived from families with at least one adult offspring.
The exposures of interest were the BMI, systolic BP (SBP) and diastolic BP (DBP) of the mother and father. The outcomes were the BMI, SBP and DBP of the offspring. Mixed-effects linear regression models were conducted.
The mean age of the offspring, mothers and fathers was 29 (SD: 9.5), 54 (SD: 11.8) and 59 (SD: 11.6) years, respectively. Father's BMI was associated with a quarter-point increase in offspring BMI, regardless of the sex of the offspring. Mother's BMI had a similar effect on the BMI of her sons, but had no significant effect on her daughters'. Mother's SBP was associated with almost one-tenth of mmHg increase in the SBP of the adult offspring. There was no evidence of an association for DBP.
In families with adult members, the higher the parents' BMI and SBP, the higher their adult offspring's levels will be.
高体重指数(BMI)和血压(BP)是导致成年期非传染性疾病负担沉重的主要因素。预防的个体高风险和人群方法需要新的策略来针对这些危险因素,并关注家庭,以引入预防措施,这似乎是一个有前途的方案。评估特定家庭中成年成员之间 BMI 和 BP 之间的关系具有重要意义。我们对秘鲁通贝斯的一项实施研究进行了二次分析,该研究受益于至少有一个成年子女的家庭的数据。
感兴趣的暴露因素是母亲和父亲的 BMI、收缩压(SBP)和舒张压(DBP)。结果是子女的 BMI、SBP 和 DBP。采用混合效应线性回归模型进行分析。
子女、母亲和父亲的平均年龄分别为 29(SD:9.5)、54(SD:11.8)和 59(SD:11.6)岁。父亲的 BMI 与子女 BMI 增加四分之一点有关,无论子女的性别如何。母亲的 BMI 对儿子的 BMI 有类似的影响,但对女儿的 BMI 没有显著影响。母亲的 SBP 与成年子女的 SBP 增加近十分之一毫米汞柱有关。DBP 没有关联的证据。
在有成年成员的家庭中,父母的 BMI 和 SBP 越高,其成年子女的水平就越高。