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天然聚合物来源的伤口敷料:基于均多糖的复合材料综述。

Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites.

机构信息

Tissue Engineering and Stem Cells Research Center, Shahroud University of Medical Sciences, Shahroud, Iran.

Institute for Molecular Bioscience, School of Chemistry & Molecular Biosciences, The University of Queensland, Brisbane, Australia.

出版信息

Carbohydr Polym. 2018 Jun 1;189:379-398. doi: 10.1016/j.carbpol.2018.02.003. Epub 2018 Feb 8.

DOI:10.1016/j.carbpol.2018.02.003
PMID:29580422
Abstract

Wound dressings are designed to support the wound bed and protect it from the factors that may delay or impede its healing such as contaminations and moisture-loss, thereby facilitating and accelerating the healing process. The materials used to prepare wound dressings include natural and synthetic polymers, as well as their combinations, in the forms of films, sponges and hydrogels. Polysaccharides are naturally-occurring polymers that have been extensively used as wound dressing materials. Homopolysaccharides are a class of polysaccharides consist of only one type of monosaccharide. The current review intends to overview the studies in which wound dressings from naturally-occurring polymers, based on homopolysaccharides, were prepared and evaluated. Homopolysaccharides such as cellulose, chitosan, chitin, pullulan, starch and β-glucan were considered.

摘要

伤口敷料旨在支持伤口床,并保护其免受可能延迟或阻碍其愈合的因素的影响,如污染和水分流失,从而促进和加速愈合过程。用于制备伤口敷料的材料包括天然和合成聚合物,以及它们的组合,形式有薄膜、海绵和水凝胶。多糖是天然存在的聚合物,已被广泛用作伤口敷料材料。均多糖是一类多糖,仅由一种单糖组成。本综述旨在概述基于均多糖的天然来源聚合物的伤口敷料的制备和评价研究。考虑了纤维素、壳聚糖、几丁质、普鲁兰、淀粉和β-葡聚糖等均多糖。

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