BPMP, Univ Montpellier, CNRS, INRA, SupAgro, Montpellier, France.
Gregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna Biocenter (VBC), Vienna, Austria.
PLoS Genet. 2018 Apr 2;14(4):e1007304. doi: 10.1371/journal.pgen.1007304. eCollection 2018 Apr.
Zinc is an essential micronutrient for all living organisms and is involved in a plethora of processes including growth and development, and immunity. However, it is unknown if there is a common genetic and molecular basis underlying multiple facets of zinc function. Here we used natural variation in Arabidopsis thaliana to study the role of zinc in regulating growth. We identify allelic variation of the systemic immunity gene AZI1 as a key for determining root growth responses to low zinc conditions. We further demonstrate that this gene is important for modulating primary root length depending on the zinc and defence status. Finally, we show that the interaction of the immunity signal azelaic acid and zinc level to regulate root growth is conserved in rice. This work demonstrates that there is a common genetic and molecular basis for multiple zinc dependent processes and that nutrient cues can determine the balance of growth and immune responses in plants.
锌是所有生物必需的微量元素，参与多种过程，包括生长和发育以及免疫。然而，目前尚不清楚是否存在一个共同的遗传和分子基础，来支撑锌的多种功能。在这里，我们利用拟南芥中的自然变异来研究锌在调节生长中的作用。我们发现系统免疫基因 AZI1 的等位基因变异是决定根对低锌条件生长反应的关键因素。我们进一步证明，该基因对于根据锌和防御状态调节主根长度很重要。最后，我们表明，免疫信号壬二酸和锌水平调控根生长的相互作用在水稻中是保守的。这项工作表明，多种依赖锌的过程存在共同的遗传和分子基础，并且营养线索可以决定植物生长和免疫反应之间的平衡。
