Laboratoire de Génétique de Maladies Rares EA7402, Institut Universitaire de Recherche Clinique, Université de Montpellier, 34000, Montpellier, France.
Laboratoire de Génétique Moléculaire, Institut Universitaire de Recherche Clinique, Centre Hospitalier Universitaire de Montpellier, 641 avenue du Doyen Gaston Giraud, 34093, Montpellier Cedex 5, France.
J Mol Evol. 2018 Apr;86(3-4):167-171. doi: 10.1007/s00239-018-9840-1. Epub 2018 Apr 5.
Simple phosphorylation, isomerization, and aldolisation reactions starting from glyceraldehyde have the potential to lead to the synthesis of pre-ribonucleotide polymers through a primitive form of the Calvin cycle (dark phase of photosynthesis) involving the unusual formation of phospho-nonulose phosphate and phospho-deculose phosphate, as key intermediates. These reactions involve activated phosphates which are generated from schreibersite minerals, geochemically available in Hadean times.
从甘油醛开始的简单磷酸化、异构化和醇醛缩合反应有可能通过涉及磷酸非核酮糖和磷酸去果糖形成的原始卡尔文循环(光合作用的暗相)来合成前核苷酸聚合物,作为关键中间体。这些反应涉及由 schreibersite 矿物产生的活化磷酸盐,这些矿物在太古代时期地球化学上是可用的。