Saratov State University, Astrakhanskaya 83, 410012, Saratov, Russia.
Saratov State University, Astrakhanskaya 83, 410012, Saratov, Russia.
Anal Chim Acta. 2018 Aug 17;1019:14-24. doi: 10.1016/j.aca.2017.12.010. Epub 2017 Dec 28.
This review covers the current state of the art of luminescent biosensors based on various types of microstructured optical fiber. The unique optical and structural properties of this type of optical fiber make them one of the most promising integrated platforms for bioassays. The individual sections of this review are devoted to a) classification of microstructured optical fibers, b) microstructured optical fiber materials, c) aspects of biosensing based on the biomolecules incorporated into the microstructured optical fibers, and d) development of models for prediction of the efficiency of luminescent signal processing. The authors' views on current trends and limitations of microstructured optical fibers for biosensing as well as the most promising areas and technologies for application in analytical practice are presented.
这篇综述涵盖了基于各种类型微结构光纤的荧光生物传感器的最新技术。这种光纤具有独特的光学和结构特性，使其成为最有前途的生物分析集成平台之一。本综述的各个部分分别涉及：a) 微结构光纤的分类，b) 微结构光纤材料，c) 基于掺入微结构光纤中的生物分子的生物传感方面，以及 d) 用于预测荧光信号处理效率的模型的开发。作者提出了对微结构光纤用于生物传感的当前趋势和限制的看法，以及在分析实践中最有前途的应用领域和技术。
