Asena Leyla, Akman Ahmet, Güngör Sirel Gür, Dursun Altınörs Dilek
a Department of Ophthalmology , Başkent University Faculty of Medicine , Ankara , Turkey.
Curr Eye Res. 2018 Jul;43(7):882-888. doi: 10.1080/02713683.2018.1458881. Epub 2018 Apr 9.
To assess agreement of a swept source-optical coherence tomography (SS-OCT) based Biometer with a standard IOLMaster device and Scheimpflug Imaging (SI) to acquire keratometric measurements in cataract patients.
In this prospective comparative study, 101 eyes of 101 cataract surgery candidates, aged 24-81 years, were sequentially examined using three devices. Keratometry values at the flat (K1) and steep (K2) axis, mean corneal power (Km) and magnitude of corneal astigmatism as well as J0 and J45 vectoral components of astigmatism obtained with the SS-OCT based biometer (IOLMaster 700) were compared with those obtained with the IOLMaster 500 and SI. The agreement between measurements was evaluated by the Bland-Altman method, intraclass correlation coefficients (ICCs) and repeated-measures analysis of variance.
Mean K1 values from the three devices were similar (p = 0.09). Mean K2 and Km values of IOLMaster 700 were higher than SI and lower than IOLMaster 500 (p = 0.04 for K2 and p = 0.02 for Km). There was a strong correlation between K1, K2, Km and magnitude of astigmatism obtained with all devices (r ≥ 0.80 and p < 0.01). The 95% limits of agreement (LoA) width for each keratometric value were highest for the comparison between IOLMaster 500 and SI and lowest for the comparison between IOLMaster 700 and 500. The mean differences (width of 95% LoA) for J0 and J45 vectoral components were 0.005 (2.19) and 0.12 (2.92) for the measurements obtained by IOLMaster 700 vs IOLMaster 500 and 0.06 (1.79) and 0.02 (1.58) for the measurements obtained by IOLMaster 700 vs SI, respectively.
With ICCs close to 1, the agreement between all devices was excellent for keratometric measurements. Mean K2, Km and astigmatism measurements from IOLMaster 700 were lower than IOLMaster 500 and higher than SI. However, the differences were quite small and are not expected to affect the final IOL power.
评估基于扫频源光学相干断层扫描（SS-OCT）的生物测量仪与标准IOLMaster设备及Scheimpflug成像（SI）在白内障患者中获取角膜曲率测量值的一致性。
在这项前瞻性比较研究中，对101例年龄在24 - 81岁的白内障手术候选者的101只眼睛依次使用三种设备进行检查。将基于SS-OCT的生物测量仪（IOLMaster 700）获得的角膜平坦（K1）和陡峭（K2）轴的角膜曲率值、平均角膜屈光力（Km）、角膜散光量以及散光的J0和J45矢量分量与IOLMaster 500和SI获得的值进行比较。通过Bland-Altman方法、组内相关系数（ICC）和重复测量方差分析评估测量之间的一致性。
三种设备的平均K1值相似（p = 0.09）。IOLMaster 700的平均K2和Km值高于SI且低于IOLMaster 500（K2的p = 0.04，Km的p = 0.02）。所有设备获得的K1、K2、Km和散光量之间存在强相关性（r≥0.80且p < 0.01）。每个角膜曲率值的95%一致性界限（LoA）宽度在IOLMaster 500和SI之间的比较中最高，在IOLMaster 700和500之间的比较中最低。IOLMaster 700与IOLMaster 500测量的J0和J45矢量分量的平均差异（95% LoA宽度）分别为0.005（2.19）和0.12（2.92），IOLMaster 700与SI测量的分别为0.06（1.79）和0.02（1.58）。
ICC接近1，所有设备在角膜曲率测量方面的一致性极佳。IOLMaster 700测量的平均K2、Km和散光低于IOLMaster 500且高于SI。然而，差异非常小，预计不会影响最终的人工晶状体屈光度。
