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基于大相干长度扫频光学相干断层扫描和谢林弗鲁格成像/部分相干干涉测量的两种光学生物测量仪之间的一致性

Agreement Between Two Optical Biometers Based on Large Coherence Length SS-OCT and Scheimpflug Imaging/Partial Coherence Interferometry.

作者信息

Tu Ruixue, Yu Jinjin, Savini Giacomo, Ye Junming, Ning Rui, Xiong Jie, Chen Sisi, Huang Jinhai

出版信息

J Refract Surg. 2020 Jul 1;36(7):459-465. doi: 10.3928/1081597X-20200420-02.

DOI:10.3928/1081597X-20200420-02
PMID:32644168
Abstract

PURPOSE

To evaluate the agreement between measurements obtained with a new optical biometer (Argos; Movu Inc) using large coherence length swept-source optical coherence tomography (SS-OCT) and those obtained with an optical biometer with a rotating Scheimpflug camera, combined with partial coherence interferometry (PCI) (Pentacam AXL; Oculus Optikgeräte GmbH) in adults.

METHODS

The following measurements were examined and evaluated: axial length, central corneal thickness (CCT), anterior chamber depth (ACD), mean keratometry, J and J vectors, and corneal diameter. Measurements with the two biometers were conducted in triplicate per instrument in a random order by the same examiner. Paired t tests were employed to compare the difference between the two devices. The Bland-Altman method was implemented to assess their agreement.

RESULTS

A total of 145 patients were enrolled in the study. The differences between the Scheimpflug/PCI-based biometer and the SS-OCT biometer were as follows: -0.02 ± 0.05 mm for axial length, 1.15 ± 5.79 µm for CCT, -0.04 ± 0.04 mm for ACD, -0.28 ± 0.16 diopters (D) for mean keratometry, 0.01 ± 0.11 D for J, -0.02 ± 0.10 D for J, and -1.03 ± 0.62 mm for corneal diameter. Bland-Altman plots showed narrow ranges in axial length, CCT, ACD, mean keratometry, and J and J, which implied excellent agreement between the two biometers. Corneal diameter displayed poor agreement, with a 95% limits of agreement ranging from -2.25 to 0.19 mm.

CONCLUSIONS

Excellent agreement was established between the measurements provided by the new optical biometer based on SS-OCT and the optical biometer using Scheimpflug imaging and PCI, except for corneal diameter. [J Refract Surg. 2020;36(7):459-465.].

摘要

目的

评估使用具有大相干长度扫频源光学相干断层扫描(SS-OCT)的新型光学生物测量仪(Argos;Movu公司)与使用旋转Scheimpflug相机结合部分相干干涉测量法(PCI)的光学生物测量仪(Pentacam AXL;Oculus Optikgeräte GmbH)在成人中所获得测量值之间的一致性。

方法

对以下测量值进行检查和评估:眼轴长度、中央角膜厚度(CCT)、前房深度(ACD)、平均角膜曲率、J和J向量以及角膜直径。由同一位检查者按照随机顺序对每台仪器的两项生物测量仪进行三次测量。采用配对t检验比较两种设备之间的差异。采用Bland-Altman方法评估它们的一致性。

结果

共有145例患者纳入本研究。基于Scheimpflug/PCI的生物测量仪与SS-OCT生物测量仪之间的差异如下:眼轴长度为-0.02±0.05mm,CCT为1.15±5.79μm,ACD为-0.04±0.04mm,平均角膜曲率为-0.28±0.16屈光度(D),J为0.01±0.11D,J为-0.02±0.10D,角膜直径为-1.03±0.62mm。Bland-Altman图显示眼轴长度、CCT、ACD、平均角膜曲率以及J和J的范围较窄,这表明两种生物测量仪之间具有极佳的一致性。角膜直径的一致性较差,95%一致性界限为-2.25至0.19mm。

结论

除角膜直径外,基于SS-OCT的新型光学生物测量仪与使用Scheimpflug成像和PCI的光学生物测量仪所提供的测量值之间建立了极佳的一致性。[《屈光手术杂志》。2020;36(7):459 - 465。]

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