Calvo-Sanz Jorge A, Portero-Benito Alejandro, Arias-Puente Alfonso
Instituto de Ciencias Visuales, INCIVI, c\ Ana Teresa, 24 - 28023, Madrid, Spain.
Ophthalmologist, Instituto de Ciencias Visuales, INCIVI, Madrid, Spain.
Graefes Arch Clin Exp Ophthalmol. 2018 Mar;256(3):559-566. doi: 10.1007/s00417-018-3909-9. Epub 2018 Feb 1.
To compare and evaluate the agreement between the measurements obtained with a swept-source optical coherence tomography (OCT)-based biometer, the IOLMaster® 700 (IOLM), and those obtained by an optical biometer based on optical low-coherence interferometry (OLCI), the Aladdin (ALD); To evaluate the ability to perform biometric measurements in those eyes with transparency alterations.
Fifty-five eyes of 55 subjects were included in this study. Axial length (AL), corneal power (K, in diopters) and its astigmatism, anterior chamber depth (ACD), central corneal thickness (CCT), and lens thickness (LT) measures were obtained within both biometers, Zeiss IOLMaster 700 and Topcon Aladdin. Results were analyzed and compared using the Student's paired samples t-test, Bland-Altman analysis and intraclass correlation coefficient (ICC).
Mean age was 73.12 ± 2.63 (62-89 years). The IOLM mean AL, K, and LT values did not show a statistically significant difference from ALD values and showed excellent agreement and correlation (ICC = 1.000, 0.970, 0.952). IOLM measured a lower mean ACD (-0.036 mm) and higher CCT measurements (9.296 μm). Those results were statistically different (p < 0.001 in both cases) but showed an excellent correlation coefficients (ICC = 0.994, 0.938). IOLM was able to obtain measures from all the eyes examined, while ALD did not measure in two cases with dense nuclear cataract. ALD showed spherical K measures in 7.27% of cases.
Overall a quite good agreement between IOLM and ALD was found. ALD showed spherical keratometry measures in 7.27% of cases. IOLMaster 700 was more effective in obtaining AL measurements in eyes with dense cataracts.
比较和评估基于扫频光学相干断层扫描（OCT）的生物测量仪IOLMaster® 700（IOLM）与基于光学低相干干涉测量法（OLCI）的光学生物测量仪阿拉丁（ALD）所获得测量值之间的一致性；评估在透明度改变的眼中进行生物测量的能力。
本研究纳入了55名受试者的55只眼睛。在蔡司IOLMaster 700和拓普康阿拉丁这两种生物测量仪中均获取了眼轴长度（AL）、角膜屈光力（K，单位为屈光度）及其散光、前房深度（ACD）、中央角膜厚度（CCT）和晶状体厚度（LT）的测量值。使用学生配对样本t检验、布兰德-奥特曼分析和组内相关系数（ICC）对结果进行分析和比较。
平均年龄为73.12±2.63岁（62 - 89岁）。IOLM的平均AL、K和LT值与ALD值相比，差异无统计学意义，且显示出极好的一致性和相关性（ICC = 1.000、0.970、0.952）。IOLM测量的平均ACD较低（-0.036 mm），CCT测量值较高（9.296 μm）。这些结果在统计学上有差异（两种情况均p < 0.001），但显示出极好的相关系数（ICC = 0.994、0.938）。IOLM能够从所有检查的眼睛中获取测量值，而ALD在两例核性白内障致密的病例中无法测量。ALD在7.27%的病例中显示出球面K测量值。
总体而言，IOLM和ALD之间有相当好的一致性。ALD在7.27%的病例中显示出球面角膜曲率测量值。IOLMaster 700在致密白内障眼中获取AL测量值方面更有效。
