Nosaka Nobuyuki, Crother Timothy R, Chen Shuang, Arditi Moshe, Shimada Kenichi
Department of Pediatrics, Division of Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Lab Anim. 2019 Feb;53(1):79-83. doi: 10.1177/0023677218765032. Epub 2018 Apr 13.
Endotracheal tube (ETT) management is an essential technique in handling mice with mechanical ventilators. Malposition into bronchi causes not only lethal complications for them but also less efficient mechanical ventilation. However, in general, it is difficult to know whether the ETT is placed with appropriate depth into the trachea of mice. We measured the distance from incisors to the bifurcation of trachea of multiple mice, and created a new estimation formula to obtain the suitable ETT length for mice with a body weight range from 17 g to 25 g: length (mm) = 0.5 × bodyweight (g) + 7. However, millimeter step adjustments are impracticable. Thus, slightly shorter than 2 cm (18-20 mm) may be the universal ETT length for mice with bodyweight > 17 g. Furthermore, their foot size may be a good alternative to predict the individual optimal ETT length for mice.
气管内插管（ETT）管理是使用机械通气器处理小鼠时的一项基本技术。误入支气管不仅会给它们带来致命并发症，还会导致机械通气效率降低。然而，一般来说，很难知道ETT是否以适当的深度插入小鼠气管。我们测量了多只小鼠从门牙到气管分叉处的距离，并创建了一个新的估算公式，以获得体重范围为17克至25克的小鼠的合适ETT长度：长度（毫米）=0.5×体重（克）+7。然而，以毫米为步长进行调整是不切实际的。因此，略短于2厘米（18 - 20毫米）可能是体重>17克小鼠的通用ETT长度。此外，它们的足尺寸可能是预测小鼠个体最佳ETT长度的一个很好的替代方法。
