Rue Emily A, Rush Michael D, van Breemen Richard B
University of Illinois College of Pharmacy, 833 S Wood St, Chicago, Il, 60612, USA.
Phytochem Rev. 2018 Feb;17(1):1-16. doi: 10.1007/s11101-017-9507-3. Epub 2017 May 9.
Procyanidins are polyphenols abundant in dietary fruits, vegetables, nuts, legumes, and grains with a variety of chemopreventive biological effects. Rapid structure determination of these compounds is needed, notably for the more complex polymeric procyanidins. We review the recent developments in the structure elucidation of procyanidins with a focus on mass spectrometric approaches, especially liquid chromatography-tandem mass spectrometry (LC-MS/MS) and matrix-assisted laser desorption ionization (MALDI) MS/MS.
原花青素是一类在膳食水果、蔬菜、坚果、豆类和谷物中含量丰富的多酚类物质,具有多种化学预防生物学效应。需要对这些化合物进行快速结构测定,尤其是对于更为复杂的聚合原花青素。我们综述了原花青素结构解析方面的最新进展,重点关注质谱方法,特别是液相色谱-串联质谱法(LC-MS/MS)和基质辅助激光解吸电离(MALDI)MS/MS。