阿根廷拉普拉塔市对含二苯甲酰甲烷防晒剂的光变应性接触性皮炎

Photoallergic Contact Dermatitis to Sunscreens Containing Oxybenzone in La Plata, Argentina.

作者信息

Russo J P, Ipiña A, Palazzolo J F, Cannavó A B, Piacentini R D, Niklasson B

机构信息

Servicio de Dermatología, Hospital San Martín de La Plata, La Plata, Argentina.

Grupo de Radiación Solar y Astropartículas, Instituto de Física Rosario, CONICET-UNR, Rosario, Argentina.

出版信息

Actas Dermosifiliogr (Engl Ed). 2018 Jul-Aug;109(6):521-528. doi: 10.1016/j.ad.2018.02.011. Epub 2018 Apr 11.

DOI:10.1016/j.ad.2018.02.011

PMID:29655482

Abstract

BACKGROUND

Photoallergic contact dermatitis (PACD) to oxybenzone was reported for the first time in 1980. Oxybenzone is the most common photoallergen in the United States and Canada and the fourth most common .in Europe. There are no studies or data on the prevalence of oxybenzone PACD in Argentina.

OBJECTIVE

To determine the proportion of photosensitive patients with PACD to oxybenzone.

METHODS

We conducted a descriptive cross-sectional study of 35 patients with photosensitivity reactions confirmed by photopatch testing at the Research Center of Hospital Público San Martín in La Plata, Argentina, in 2015 and 2016.

RESULTS

PACD was identified in 6 patients (17.14%). Five of these (14.28%) had at least one positive reaction to oxybenzone in the photopatch test; 4 had a reaction at irradiated sites only (5 J/cm UVA) and one had a reaction at both irradiated and nonirradiated sites.

CONCLUSIONS

PACD to sunscreens containing oxybenzone is common and is probably underdiagnosed due to a lack of confirmation by photopatch tests or other diagnostic tools. Sensitization rates vary according to region and are influenced by sunscreen ingredients and variations in the use of sunscreen products, cosmetics, and topical drugs.

摘要