University of California, San Francisco-University of California Berkeley Joint Medical Program, Berkeley, USA.
Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, USA.
Curr Allergy Asthma Rep. 2018 Apr 16;18(5):29. doi: 10.1007/s11882-018-0782-x.
Given racial disparities in ambient air pollution (AAP) exposure and asthma risk, this review offers an overview of the literature investigating the ambient air pollution-asthma relationship in children of color between 2013 and 2017.
AAP is likely a key contributor to the excess burden of asthma in children of color due to pervasive exposure before birth, at home, and in school. Recent findings suggest that psychosocial stressors may modify the relationship between AAP and asthma. The effect of AAP on asthma in children of color is likely modulated by multiple unique psychosocial stressors and gene-environment interactions. Although children of color are being included in asthma studies, more research is still needed on impacts of specific criteria pollutants throughout the life course. Additionally, future studies should consider historical factors when analyzing current exposure profiles.
综述目的:鉴于环境空气污染(AAP)暴露和哮喘风险方面存在种族差异,本综述概述了 2013 年至 2017 年间针对有色人种儿童的环境空气污染与哮喘之间关系的文献研究。
最新发现:由于在产前、家庭中和学校中普遍存在暴露,AAP 可能是导致有色人种儿童哮喘负担过重的一个关键因素。最近的研究结果表明,心理社会压力因素可能会改变 AAP 与哮喘之间的关系。AAP 对有色人种儿童哮喘的影响可能受到多种独特的心理社会压力因素和基因-环境相互作用的调节。尽管有色人种儿童被纳入哮喘研究中,但在整个生命周期中,仍需要更多关于特定标准污染物影响的研究。此外,未来的研究在分析当前暴露情况时应考虑历史因素。