Burbank Allison J, Peden David B
Department of Pediatrics, Division of Allergy, Immunology & Rheumatology, University of North Carolina, Chapel Hill, North Carolina, USA.
Curr Opin Allergy Clin Immunol. 2018 Apr;18(2):124-131. doi: 10.1097/ACI.0000000000000422.
Exposure to air pollutants is linked with poor asthma control in children and represents a potentially modifiable risk factor for impaired lung function, rescue medication use, and increased asthma-related healthcare utilization. Identification of the most relevant pollutants to asthma as well as susceptibility factors and strategies to reduce exposure are needed to improve child health.
The current available literature supports the association between pollutants and negative asthma outcomes. Ethnicity, socioeconomic status, and presence of certain gene polymorphisms may impact susceptibility to the negative health effects of air pollution. Improved air quality standards were associated with better asthma outcomes.
The link between air pollution and pediatric asthma morbidity is supported by the recent relevant literature. Continued efforts are needed to identify the most vulnerable populations and develop strategies to reduce exposures and improve air quality.
接触空气污染物与儿童哮喘控制不佳有关，是肺功能受损、使用急救药物以及增加哮喘相关医疗保健利用率的一个潜在可改变风险因素。为改善儿童健康状况，需要确定与哮喘最相关的污染物以及易感性因素和减少接触的策略。
现有文献支持污染物与哮喘不良结局之间的关联。种族、社会经济地位和某些基因多态性的存在可能影响对空气污染负面健康影响的易感性。空气质量标准的改善与更好的哮喘结局相关。
近期相关文献支持空气污染与儿童哮喘发病率之间的联系。需要持续努力确定最脆弱人群，并制定减少接触和改善空气质量的策略。
