J Orthop Sports Phys Ther. 2018 Jun;48(6):439-447. doi: 10.2519/jospt.2018.7877. Epub 2018 Apr 18.
Synopsis Osteoarthritis (OA) of the hip and knee is among the leading causes of global disability, highlighting the need for early, targeted, and effective treatment. The benefits of exercise therapy in people with hip and knee OA are substantial and supported by high-quality evidence, underlining that it should be part of first-line treatment in clinical practice. Furthermore, unlike other treatments for OA, such as analgesia and surgery, exercise therapy is not associated with risk of serious harm. Helping people with OA become more physically active, along with structured exercise therapy targeting symptoms and impairments, is crucial, considering that the majority of people with hip and knee OA do not meet physical activity recommendations. Osteoarthritis is associated with a range of chronic comorbidities, including type 2 diabetes, cardiovascular disease, and dementia, all of which are associated with chronic low-grade inflammation. Physical activity and exercise therapy not only improve symptoms and impairments of OA, but are also effective in preventing at least 35 chronic conditions and treating at least 26 chronic conditions, with one of the potential working mechanisms being exercise-induced anti-inflammatory effects. Patient education may be crucial to ensure long-term adherence and sustained positive effects on symptoms, impairments, physical activity levels, and comorbidities. J Orthop Sports Phys Ther 2018;48(6):439-447. Epub 18 Apr 2018. doi:10.2519/jospt.2018.7877.
概要 髋和膝关节骨关节炎（OA）是全球致残的主要原因之一，这凸显了早期、有针对性和有效的治疗的必要性。运动疗法对髋和膝关节 OA 患者的益处是巨大的，有高质量证据支持，这表明它应该成为临床实践中一线治疗的一部分。此外，与其他 OA 治疗方法（如镇痛和手术）不同，运动疗法不会带来严重伤害的风险。帮助 OA 患者变得更加活跃，同时进行针对症状和功能障碍的结构化运动疗法，至关重要，因为大多数髋和膝关节 OA 患者不符合身体活动建议。OA 与一系列慢性合并症有关，包括 2 型糖尿病、心血管疾病和痴呆，所有这些都与慢性低度炎症有关。身体活动和运动疗法不仅可以改善 OA 的症状和功能障碍，而且还可以有效预防至少 35 种慢性疾病，并治疗至少 26 种慢性疾病，其潜在的作用机制之一是运动引起的抗炎作用。患者教育可能是确保长期坚持和对症状、功能障碍、身体活动水平和合并症持续产生积极影响的关键。《矫形与运动物理治疗杂志》2018 年；48(6):439-447. 2018 年 4 月 18 日在线发表。doi:10.2519/jospt.2018.7877.
