铕（III）配位络合物的对映选择性细胞定位
Enantioselective cellular localisation of europium(iii) coordination complexes.
作者信息
Frawley Andrew T, Linford Holly V, Starck Matthieu, Pal Robert, Parker David
机构信息
Department of Chemistry , Durham University , South Road , Durham , DH1 3LE , UK . Email:
出版信息
Chem Sci. 2017 Dec 6;9(4):1042-1049. doi: 10.1039/c7sc04422d. eCollection 2018 Jan 28.
Abstract
The selective mitochondrial localisation of the enantiomer of three different emissive europium(iii) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs macropinocytosis.
摘要
三种不同发光铕（III）配合物的对映体在NIH 3T3和MCF7细胞中的选择性线粒体定位与该对映体的行为形成对比，通过共聚焦显微镜观察到该对映体主要定位于溶酶体。在每种情况下，细胞摄取都是通过巨胞饮作用发生的。
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