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铕（III）配位络合物的对映选择性细胞定位

Enantioselective cellular localisation of europium(iii) coordination complexes.

作者信息

Frawley Andrew T, Linford Holly V, Starck Matthieu, Pal Robert, Parker David

机构信息

Department of Chemistry , Durham University , South Road , Durham , DH1 3LE , UK . Email:

出版信息

Chem Sci. 2017 Dec 6;9(4):1042-1049. doi: 10.1039/c7sc04422d. eCollection 2018 Jan 28.

DOI:10.1039/c7sc04422d
PMID:29675151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5883863/
Abstract

The selective mitochondrial localisation of the enantiomer of three different emissive europium(iii) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs macropinocytosis.

摘要

三种不同发光铕（III）配合物的对映体在NIH 3T3和MCF7细胞中的选择性线粒体定位与该对映体的行为形成对比，通过共聚焦显微镜观察到该对映体主要定位于溶酶体。在每种情况下，细胞摄取都是通过巨胞饮作用发生的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/beb6ac294486/c7sc04422d-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/188db049be58/c7sc04422d-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/07eab4049a8b/c7sc04422d-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/3f77f5e8955c/c7sc04422d-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/f61f58947542/c7sc04422d-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/21c7b7232d4b/c7sc04422d-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/beb6ac294486/c7sc04422d-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/188db049be58/c7sc04422d-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/07eab4049a8b/c7sc04422d-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/3f77f5e8955c/c7sc04422d-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/f61f58947542/c7sc04422d-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/21c7b7232d4b/c7sc04422d-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e258/5883863/beb6ac294486/c7sc04422d-f5.jpg

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