Murch Randall S, So William K, Buchholz Wallace G, Raman Sanjay, Peccoud Jean
Virginia Tech - National Capital Region, Virginia Polytechnic Institute and State University, Arlington, VA, United States.
Weapons of Mass Destruction Directorate, Federal Bureau of Investigation, Washington, DC, United States.
Front Bioeng Biotechnol. 2018 Apr 5;6:39. doi: 10.3389/fbioe.2018.00039. eCollection 2018.
Cyberbiosecurity is being proposed as a formal new enterprise which encompasses cybersecurity, cyber-physical security and biosecurity as applied to biological and biomedical-based systems. In recent years, an array of important meetings and public discussions, commentaries and publications have occurred that highlight numerous vulnerabilities. While necessary first steps, they do not provide a systematized structure for effectively promoting communication, education and training, elucidation and prioritization for analysis, research, development, test and evaluation and implementation of scientific, technological, standards of practice, policy, or even regulatory or legal considerations for protecting the bioeconomy. Further, experts in biosecurity and cybersecurity are generally not aware of each other's domains, expertise, perspectives, priorities, or where mutually supported opportunities exist for which positive outcomes could result. Creating, promoting and advancing a new discipline can assist with formal, beneficial and continuing engagements. Recent key activities and publications that inform the creation of Cyberbiosecurity are briefly reviewed, as is the expansion of Cyberbiosecurity to include biomanufacturing which is supported by a rigorous analysis of a biomanufacturing facility. Recommendations are provided to initialize Cyberbiosecurity and place it on a trajectory to establish a structured and sustainable discipline, forum and enterprise.
网络生物安全正被提议作为一个正式的新领域，它涵盖了应用于基于生物和生物医学的系统的网络安全、网络物理安全和生物安全。近年来，一系列重要会议、公开讨论、评论和出版物纷纷涌现，突出了众多漏洞。虽然这些是必要的初步措施，但它们并未提供一个系统化的架构，以有效地促进沟通、教育与培训，阐明并确定分析、研究、开发、测试与评估的优先级，以及实施科学、技术、实践标准、政策，甚至是保护生物经济的监管或法律考量。此外，生物安全和网络安全领域的专家通常并不了解彼此的领域、专业知识、观点、优先事项，也不清楚哪些地方存在相互支持且能产生积极成果的机会。创建、推广和推进一门新学科有助于进行正式、有益且持续的参与。本文简要回顾了为网络生物安全的创建提供信息的近期关键活动和出版物，以及网络生物安全向包括生物制造的扩展，这一扩展得到了对一个生物制造设施的严格分析的支持。文中还提供了相关建议，以启动网络生物安全并使其走上建立一个结构化且可持续的学科、论坛和领域的轨道。
