Department of Dermatology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Department of Dermatology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
J Dermatol. 2018 Jul;45(7):755-780. doi: 10.1111/1346-8138.14161. Epub 2018 Apr 23.
We established diagnostic criteria and severity classification of localized scleroderma because there is no established diagnostic criteria or widely accepted severity classification of the disease. Also, there has been no clinical guideline for localized scleroderma, so we established its clinical guideline ahead of all over the world. In particular, the clinical guideline was established by clinical questions based on evidence-based medicine according to the New Minds Clinical Practice Guideline Creation Manual (version 1.0). We aimed to make the guideline easy to use and reliable based on the newest evidence, and to present guidance as specific as possible for various clinical problems in treatment of localized scleroderma.
我们制定了局限性硬皮病的诊断标准和严重程度分类，因为目前还没有确立的诊断标准或广泛接受的疾病严重程度分类。此外，局限性硬皮病也没有临床指南，因此我们在全世界率先制定了其临床指南。特别是，该临床指南是根据循证医学基于新思维临床实践指南制定手册（第 1.0 版）的临床问题制定的。我们旨在根据最新的证据使该指南易于使用和可靠，并为局限性硬皮病的各种临床问题提供尽可能具体的指导。
