Kreuter Alexander, Krieg Thomas, Worm Margitta, Wenzel Jörg, Moinzadeh Pia, Kuhn Annegret, Aberer Elisabeth, Scharffetter-Kochanek Karin, Horneff Gerd, Reil Emma, Weberschock Tobias, Hunzelmann Nicolas
Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital Oberhausen, Oberhausen, Germany.
Department of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany.
J Dtsch Dermatol Ges. 2016 Feb;14(2):199-216. doi: 10.1111/ddg.12724.
Localized scleroderma designates a heterogeneous group of sclerotic skin disorders. Depending on the subtype, severity, and site affected, adjacent structures such as adipose tissue, muscles, joints, and bones may be involved. This is an update of the existing German AWMF (Association of the Scientific Medical Societies in Germany) guidelines (classification: S2k). These guidelines provide an overview of the definition, epidemiology, classification, pathogenesis, laboratory workup, histopathology, clinical scoring systems, as well as imaging and device-based workup of localized scleroderma. Moreover, consensus-based recommendations are given on the management of localized scleroderma depending on its clinical subtype. Treatment recommendations are presented in a therapeutic algorithm. No financial support was given by any pharmaceutical company. The guidelines are valid until July 2019.
局限性硬皮病指的是一组硬化性皮肤疾病的异质性群体。根据亚型、严重程度和受累部位，相邻结构如脂肪组织、肌肉、关节和骨骼可能会受到累及。这是对现有的德国医学科学协会联合会（AWMF）指南（分类：S2k）的更新。这些指南概述了局限性硬皮病的定义、流行病学、分类、发病机制、实验室检查、组织病理学、临床评分系统以及影像学和基于设备的检查。此外，根据临床亚型对局限性硬皮病的管理给出了基于共识的建议。治疗建议以治疗算法的形式呈现。没有任何制药公司提供资金支持。这些指南有效期至2019年7月。
