Bondu M, Marques M J, Moselund P M, Lall G, Bradu A, Podoleanu A
University of Kent, Applied Optics Group, School of Physical Sciences, Ingram building, Canterbury CT2 7NH, United Kingdom.
NKT Photonics A/S, Blokken 84, Birkeroed 3460, Denmark.
Photoacoustics. 2017 Nov 26;9:21-30. doi: 10.1016/j.pacs.2017.11.002. eCollection 2018 Mar.
We report on the use of a single supercontinuum (SC) source for multimodal imaging. The 2-octave bandwidth (475-2300 nm) makes the SC source suitable for optical coherence tomography (OCT) as well as for multispectral photoacoustic microscopy (MPAM). The IR band centered at 1310 nm is chosen for OCT to penetrate deeper into tissue with 8 mW average power on the sample. The 500-840 nm band is used for MPAM. The source has the ability to select the central wavelength as well as the spectral bandwidth. An energy of more than 35 nJ within a less than 50 nm bandwidth is achieved on the sample for wavelengths longer than 500 nm. In the present paper, we demonstrate the capabilities of such a multimodality imaging instrument based on a single optical source. mouse ear B-scan images are presented.
我们报告了使用单个超连续谱（SC）源进行多模态成像的情况。2倍频程带宽（475 - 2300纳米）使该SC源适用于光学相干断层扫描（OCT）以及多光谱光声显微镜（MPAM）。选择以1310纳米为中心的红外波段用于OCT，以便以8毫瓦的平均样品功率更深地穿透组织。500 - 840纳米波段用于MPAM。该源能够选择中心波长以及光谱带宽。对于波长大于500纳米的情况，在样品上实现了在小于50纳米带宽内超过35纳焦的能量。在本文中，我们展示了基于单个光源的这种多模态成像仪器的性能。展示了小鼠耳部的B扫描图像。
