Graduate Program in Medical Sciences, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Graduate Program in Biosciences and Technology of Bioactive Products, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.
Phytother Res. 2018 Sep;32(9):1664-1674. doi: 10.1002/ptr.6102. Epub 2018 May 2.
Nature has been a source of medicinal treatments for thousands of years, with the use of plants as prototypes for drug development and for the extraction of active compounds. Skin injuries occur regularly in everyday life, and the human skin has the ability to promote repair spontaneously under healthy conditions. However, some intrinsic and external factors may interfere with skins' natural ability, leading to nonhealing lesions and chronic wounds, which directly affect health and quality of life. Thus, attention should be given to this health problem, using an appropriated management when necessary. In this scenario, phytotherapy may be an option for cutaneous wound treatment, although further high-quality studies are needed to firmly establish the clinical efficacy of plants. This article reviews traditionally used natural actives for wound healing, highlighting their characteristics and mode of action.
千百年来，大自然一直是医学治疗的来源，人们利用植物作为药物开发和提取活性化合物的原型。日常生活中皮肤损伤很常见，在健康的条件下，人类皮肤有自行促进修复的能力。然而，一些内在和外在因素可能会干扰皮肤的自然能力，导致伤口无法愈合和慢性伤口，这直接影响健康和生活质量。因此，应该关注这个健康问题，在必要时进行适当的管理。在这种情况下，植物疗法可能是治疗皮肤伤口的一种选择，尽管还需要更多高质量的研究来确定植物的临床疗效。本文综述了传统上用于伤口愈合的天然活性剂，强调了它们的特性和作用机制。
