Max-Planck-Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam-Golm, 14476, Germany.
Centre of Plant System Biology and Biotechnology, Plovdiv, 4000, Bulgaria.
Plant J. 2018 Jun;94(6):933-942. doi: 10.1111/tpj.13950.
The term metabolome was coined in 1998, by analogy to genome, transcriptome and proteome. The first research papers using the terms metabolomics, metabonomics, metabolic profiling or metabolite profiling were published shortly thereafter. In this short review we reflect on the major achievements brought about by the use of these approaches, and document the knowledge and technology gaps that are currently constraining its further development. Finally, we detail why we think that the time is ripe to refocus our efforts on the understanding of metabolic function.
“代谢组学”这一术语是在 1998 年提出的，其命名方式类似于基因组学、转录组学和蛋白质组学。此后不久，便有了第一批使用代谢组学、代谢组分析、代谢轮廓分析或代谢物轮廓分析等术语的研究论文发表。在这篇简短的综述中，我们反思了使用这些方法所带来的主要成就，并记录了目前限制其进一步发展的知识和技术差距。最后，我们详细说明了为什么我们认为现在是重新集中精力理解代谢功能的时候了。
