Division of Bioengineering and Bioinformatics, Graduate School of Information Science and Technology, Hokkaido University, Hokkaido, Japan.
Computer Science Laboratory, Comprehensive Research Organization, Fukuoka Institute of Technology, Fukuoka, Japan.
Sci Rep. 2018 May 8;8(1):7298. doi: 10.1038/s41598-018-25681-5.
Cuffless blood pressure (BP) measurement is an all-inclusive term for a method that aims to measure BP without using a cuff. Recent cuffless technology has made it possible to estimate BP with reasonable accuracy. However, mainstream methods require an electrocardiogram and photoplethysmogram measurements, and frequent calibration procedures using a cuff sphygmomanometer. We therefore developed a far simpler cuffless method, using only heart rate (HR) and modified normalized pulse volume (mNPV) that can be measured using a smartphone, based on the knowledge that ln BP = ln cardiac output (CO) + ln total peripheral resistance (TPR), where CO and TPR are correlated with HR and mNPV, respectively. Here, we show that mean arterial pressure (MAP), systolic BP (SBP), and diastolic BP (DBP) could be estimated using the exponential transformation of linear polynomial equation, (a × ln HR) + (b × ln mNPV) + constant, using only a smartphone, with an accuracy of R > 0.70. This implies that our cuffless method could convert a large number of smartphones or smart watches into simplified sphygmomanometers.
无袖带血压(BP)测量是指一种无需使用袖带即可测量血压的方法的统称。最近的无袖带技术已经使得以合理的精度估计血压成为可能。然而,主流方法需要心电图和光体积描记法测量,并经常使用袖带血压计进行校准程序。因此,我们仅使用心率(HR)和改良的归一化脉搏体积(mNPV)开发了一种更为简单的无袖带方法,该方法可以使用智能手机进行测量,其依据是 ln BP = ln 心输出量(CO)+ln 总外周阻力(TPR),其中 CO 和 TPR 分别与 HR 和 mNPV 相关。在这里,我们表明,仅使用智能手机,通过线性多项式方程的指数变换(a×ln HR)+(b×ln mNPV)+常数,可以估计平均动脉压(MAP)、收缩压(SBP)和舒张压(DBP),其准确性为 R > 0.70。这意味着我们的无袖带方法可以将大量智能手机或智能手表转换为简化的血压计。