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高免赔额保险对乳腺癌辅助激素治疗使用的影响。

Impact of high-deductible insurance on adjuvant hormonal therapy use in breast cancer.

机构信息

Division of Health Policy and Insurance Research, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 401 Park Drive, Suite 401 East, Boston, MA, 02215, USA.

Department of Medicine, Brigham & Women's Hospital, 800 Huntington Avenue, Boston, MA, 02115, USA.

出版信息

Breast Cancer Res Treat. 2018 Aug;171(1):235-242. doi: 10.1007/s10549-018-4821-z. Epub 2018 May 12.

Abstract

OBJECTIVE

High-deductible health plans (HDHPs) have become the predominant commercial health insurance arrangement in the US. HDHPs require substantial out-of-pocket (OOP) costs for most services but often exempt medications from high cost sharing. We examined effects of HDHPs on OOP costs and utilization of adjuvant hormonal therapy (AHT), which are fundamental care for patients with breast cancer.

METHODS

This controlled quasi-experimental study used claims data (2003-2012) from a large national health insurer. We included 986 women with incident early-stage breast cancer, age 25-64 years, insured by employers that mandated a transition from low-deductible (≤ $500/year) to high-deductible (≥ $1000/year) coverage, and 3479 propensity score-matched controls whose employers offered only low-deductible plans. We examined AHT utilization and OOP costs per person-year before and after the HDHP switch.

RESULTS

At baseline, the OOP costs for AHT were $40.41 and $36.55 per person-year among the HDHP and control groups. After the HDHP switch, the OOP costs for AHT were $91.76 and $72.98 per person-year among the HDHP and control groups, respectively. AHT OOP costs increased among HDHP members relative to controls but the change was not significant (relative change 13.72% [95% CI - 9.25, 36.70%]). AHT use among HDHP members did not change compared to controls (relative change of 2.73% [95% CI - 14.01, 19.48%]); the change in aromatase inhibitor use was - 11.94% (95% CI - 32.76, 8.88%) and the change in tamoxifen use was 20.65% (95% CI - 8.01, 49.32%).

CONCLUSION

We did not detect significant changes in AHT use after the HDHP switch. Findings might be related to modest increases in overall AHT OOP costs, the availability of low-cost generic tamoxifen, and patient awareness that AHT can prolong life and health. Minimizing OOP cost increases for essential medications might represent a feasible approach for maintaining medication adherence among HDHP members with incident breast cancer.

摘要

目的

高免赔额健康计划(HDHPs)已成为美国主要的商业健康保险安排。HDHPs 对大多数服务都要求大量自付费用(OOP),但通常免除药物的高额共付额。我们研究了 HDHPs 对 OOP 成本和辅助激素治疗(AHT)使用的影响,AHT 是乳腺癌患者基本护理的关键。

方法

本对照准实验研究使用了一家大型全国健康保险公司的索赔数据(2003-2012 年)。我们纳入了 986 名患有早期乳腺癌的女性,年龄在 25-64 岁之间,受雇于雇主,雇主强制从低免赔额(≤500 美元/年)过渡到高免赔额(≥1000 美元/年)的保险,3479 名与之相匹配的倾向评分对照组,其雇主仅提供低免赔额计划。我们检查了 HDHP 转换前后个人每年的 AHT 使用率和 OOP 成本。

结果

在基线时,HDHP 组和对照组的 AHT OOP 成本分别为每人每年 40.41 美元和 36.55 美元。在 HDHP 转换后,HDHP 组和对照组的 AHT OOP 成本分别为每人每年 91.76 美元和 72.98 美元。与对照组相比,HDHP 成员的 AHT OOP 成本增加,但变化不显著(相对变化 13.72%[-9.25,36.70%])。与对照组相比,HDHP 成员的 AHT 使用量没有变化(相对变化 2.73%[-14.01,19.48%]);芳香化酶抑制剂的使用减少了 11.94%[-32.76,8.88%],而他莫昔芬的使用增加了 20.65%[-8.01,49.32%]。

结论

我们没有发现 HDHP 转换后 AHT 使用的显著变化。这一发现可能与整体 AHT OOP 成本的适度增加、低价仿制药的可获得性以及患者对 AHT 可以延长生命和健康的认识有关。尽量减少基本药物的 OOP 成本增加可能是维持 HDHP 中患有乳腺癌的患者用药依从性的一种可行方法。

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Breast Cancer Diagnosis and Treatment After High-Deductible Insurance Enrollment.参保高免赔额保险后对乳腺癌的诊断和治疗
J Clin Oncol. 2018 Apr 10;36(11):1121-1127. doi: 10.1200/JCO.2017.75.2501. Epub 2018 Feb 28.

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