Sidari Anthony, Hill Erica
San Antonio Uniformed Services Health Consortium, Department of Rheumatology, 3851 Roger Brooke Drive, San Antonio, TX 78234, USA.
San Antonio Uniformed Services Health Consortium, Department of Rheumatology, 3851 Roger Brooke Drive, San Antonio, TX 78234, USA.
Prim Care. 2018 Jun;45(2):213-236. doi: 10.1016/j.pop.2018.02.004.
Gout and pseudogout are crystalline arthropathies commonly seen in primary care. It is important to understand their pathophysiology to facilitate recognition and appropriate treatment. Prompt gouty arthritis treatment relieves short-term suffering. Long-term treatment with urate-lowering therapy prevents recurrent attacks and is generally well-tolerated though flare risk is increased during treatment initiation. When anti-inflammatory medications are prescribed, the flare risk is low. Pseudogout acute treatment is similar to acute gouty arthritis treatment. There is no standard regimen for long-term chronic therapies of pseudogout. This article enhances the recognition and treatment of these diseases in the primary care setting.
痛风和假性痛风是基层医疗中常见的结晶性关节病。了解它们的病理生理学对于促进识别和恰当治疗很重要。及时的痛风性关节炎治疗可缓解短期痛苦。使用降尿酸疗法进行长期治疗可预防复发,虽然在治疗开始时发作风险会增加,但一般耐受性良好。开具抗炎药物时,发作风险较低。假性痛风的急性治疗与急性痛风性关节炎的治疗相似。假性痛风的长期慢性治疗尚无标准方案。本文旨在提高基层医疗环境中对这些疾病的识别和治疗水平。