Jóźków Paweł, Koźlenia Dawid, Zawadzka Katarzyna, Konefał Marek, Chmura Paweł, Młynarska Katarzyna, Kosowski Michał, Mędraś Marek, Chmura Jan, Ponikowski Piotr, Daroszewski Jacek
Department of Sports Medicine and Dietetics, Wroclaw University of Physical Education, Ul. I.J. Paderewskiego 35, 51-612, Wrocław, Poland.
Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, L. Pasteur 4, 50-367, Wrocław, Poland.
J Physiol Sci. 2019 Jan;69(1):79-84. doi: 10.1007/s12576-018-0619-3. Epub 2018 May 14.
Our aim was to verify whether running a marathon is associated with changes in irisin concentration in healthy, endurance-trained men. In an observational study, we assessed baseline biochemical and fitness parameters of 28 middle-aged runners (mean ± SD age, BMI, VO: 58 ± 8 years; 24.5 ± 3 kg/m; 51.1 ± 1.7 ml/kg/min). We evaluated irisin before, immediately after, and 7 days after the marathon. Irisin concentration decreased from a baseline value of 639 ± 427 to 461 ± 255 ng/ml immediately after the marathon (p < 0.05). After 7 days, it was still significantly lower than before the race, at 432 ± 146 ng/ml (p < 0.05). We found no correlations between irisin concentration and the training history of the studied subjects. We conclude that a long-distance run may have a negative impact on irisin release in men. This effect was not correlated with the training history of runners.
我们的目的是验证马拉松跑步是否与健康的、有耐力训练的男性鸢尾素浓度变化有关。在一项观察性研究中，我们评估了28名中年跑步者的基线生化和体能参数（平均±标准差年龄、体重指数、最大摄氧量：58±8岁；24.5±3kg/m²；51.1±1.7ml/kg/min）。我们在马拉松比赛前、比赛后即刻以及比赛后7天对鸢尾素进行了评估。马拉松比赛后即刻，鸢尾素浓度从基线值639±427降至461±255ng/ml（p<0.05）。7天后，其仍显著低于比赛前，为432±146ng/ml（p<0.05）。我们发现鸢尾素浓度与所研究对象的训练史之间没有相关性。我们得出结论，长跑可能会对男性鸢尾素的释放产生负面影响。这种影响与跑步者的训练史无关。
