Hotel Dieu de France, A. Naccache boulevard, Achrafieh, P.O. Box 166830, Beirut, Lebanon.
Saint Joseph University, Beirut, Lebanon.
Eat Weight Disord. 2020 Feb;25(1):79-86. doi: 10.1007/s40519-018-0512-3. Epub 2018 May 15.
Eating disorders (ED) are prevalent mental illnesses composed mainly of anorexia nervosa, bulimia nervosa and binge eating disorders. Anxiety disorders are another set of mental illnesses, with phobic disorder (PD) being the most prevalent disorder. ED and PD are highly comorbid. The aim of this study is to assess, in 131 individuals attending an outpatient clinic for different health issues, the level of fear related to situations generating avoidance such as in social anxiety and specific phobias according to the fear questionnaire (FQ), the level of disgust according to the disgust scale (DS-R) and the vulnerability towards ED according to the SCOFF scale to demonstrate that high levels of both fear and disgust increase the vulnerability towards ED. The study demonstrated that the level of disgust increased when fear increases (r = 0.377, p < 0.001 for the first part of the FQ; r = 0.225, p = 0.01 for the second part of the FQ). Moreover, individuals with vulnerability towards having an ED presented a higher level of disgust than individuals without this vulnerability (p = 0.009). Furthermore, individuals with vulnerability towards ED have a higher level of anxiety related to PD subtypes (p = 0.008 for agoraphobia; p = 0.001 for injection/blood phobia) as well as to social anxiety (p = 0.01), independently from having a depressive or another anxiety disorder. In the multivariate analysis, a history of psychiatric consultation has been the only significantly different parameter between individuals with or without vulnerability towards ED (p = 0.0439). Accordingly, fear and disgust are negative emotions that seem to be clinically associated which better explains the comorbidity of ED with PD. LEVEL OF EVIDENCE: Level III. Evidence obtained from well-designed cohort or case-control analytic studies, preferably from more than one center or research group.
进食障碍（ED）是常见的精神疾病，主要包括神经性厌食症、神经性贪食症和暴食障碍。焦虑障碍是另一组精神疾病，其中恐惧症（PD）是最常见的疾病。ED 和 PD 高度共病。本研究旨在评估 131 名在门诊就诊的不同健康问题的个体，根据恐惧问卷（FQ）评估与社交焦虑和特定恐惧症相关的回避情况的恐惧程度，根据厌恶量表（DS-R）评估厌恶程度，以及根据 SCOFF 量表评估对 ED 的易感性，以证明恐惧和厌恶程度的增加都会增加对 ED 的易感性。研究表明，当恐惧增加时，厌恶程度也会增加（FQ 第一部分的 r 值为 0.377，p<0.001；FQ 第二部分的 r 值为 0.225，p=0.01）。此外，有 ED 易感性的个体比没有这种易感性的个体表现出更高的厌恶水平（p=0.009）。此外，有 ED 易感性的个体对 PD 亚型（广场恐怖症，p=0.008；注射/血液恐惧症，p=0.001）以及社交焦虑（p=0.01）的焦虑程度更高，而与是否患有抑郁或其他焦虑障碍无关。在多变量分析中，精神科就诊史是有或没有 ED 易感性个体之间唯一有显著差异的参数（p=0.0439）。因此，恐惧和厌恶是两种负面情绪，它们似乎在临床上存在关联，这更好地解释了 ED 与 PD 的共病。证据等级：III 级。来自设计良好的队列或病例对照分析研究的证据，最好来自多个中心或研究小组。
