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如何监测实验用啮齿动物的呼吸:当前方法综述

How to monitor breathing in laboratory rodents: a review of the current methods.

作者信息

Grimaud Julien, Murthy Venkatesh N

机构信息

Department of Molecular and Cellular Biology and Center for Brain Science, Harvard University , Cambridge, Massachusetts.

出版信息

J Neurophysiol. 2018 Aug 1;120(2):624-632. doi: 10.1152/jn.00708.2017. Epub 2018 May 23.

Abstract

Accurately measuring respiration in laboratory rodents is essential for many fields of research, including olfactory neuroscience, social behavior, learning and memory, and respiratory physiology. However, choosing the right technique to monitor respiration can be tricky, given the many criteria to take into account: reliability, precision, and invasiveness, to name a few. This review aims to assist experimenters in choosing the technique that will best fit their needs, by surveying the available tools, discussing their strengths and weaknesses, and offering suggestions for future improvements.

摘要

准确测量实验用啮齿动物的呼吸对于许多研究领域至关重要,包括嗅觉神经科学、社会行为、学习与记忆以及呼吸生理学。然而,鉴于需要考虑诸多标准,如可靠性、精度和侵入性等,选择合适的呼吸监测技术可能颇具难度。本综述旨在通过调研现有工具、讨论其优缺点并为未来改进提供建议,帮助实验人员选择最符合其需求的技术。

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