Akashi Natsuki, Miyagawa Yui, Kuno Hiroaki, Eto Masumi, Akagi Tetsuya
Department of Veterinary Medicine, Faculty of Veterinary Medicine, Okayama University of Science, Ehime, Japan.
Department of Information Science and Engineering, Faculty of Information Science and Engineering, Okayama University of Science, Okayama, Japan.
J Vet Med Sci. 2025 Feb 4;87(2):175-180. doi: 10.1292/jvms.24-0457. Epub 2024 Dec 31.
Respiratory rate monitoring is essential especially for anesthetized animals in veterinary and biomedical research. Current methods often rely on invasive or wearable devices, which can stress animals, especially smaller ones like rodents. Here we present a non-invasive, environmentally integrated device that detects subtle breathing movements through waveform analyzed data via a triaxial accelerometer under a flexible fabric sheet in a trampoline-like box. The accuracy of the system was tested on anesthetized mice under varying isoflurane concentrations (1 to 3%) by comparison with a laser displacement sensor. The accelerometer data closely correlated with that from a laser displacement sensor, particularly under deeper anesthesia, with minimal deviations in respiratory rate detection. This method may provide a promising alternative for animal respiratory monitoring.
呼吸频率监测至关重要，特别是在兽医和生物医学研究中对麻醉动物而言。当前的方法通常依赖侵入性或可穿戴设备，这可能会给动物带来压力，尤其是像啮齿动物这样的小型动物。在此，我们展示了一种非侵入性的、与环境整合的设备，该设备通过一个类似蹦床的盒子中柔性织物片下的三轴加速度计，通过分析波形数据来检测细微的呼吸运动。通过与激光位移传感器比较，在不同异氟烷浓度（1%至3%）下对麻醉小鼠测试了该系统的准确性。加速度计数据与激光位移传感器的数据密切相关，特别是在深度麻醉下，呼吸频率检测的偏差最小。这种方法可能为动物呼吸监测提供一种有前景的替代方案。
