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出生时母亲年龄对新生儿死亡率的影响:来自 45 个低收入和中等收入国家的证据。

The impact of young maternal age at birth on neonatal mortality: Evidence from 45 low and middle income countries.

机构信息

Department of Social Statistics and Demography, University of Southampton, Southampton, United Kingdom.

Chancellor College, University of Malawi, Zomba, Malawi.

出版信息

PLoS One. 2018 May 23;13(5):e0195731. doi: 10.1371/journal.pone.0195731. eCollection 2018.

Abstract

OBJECTIVES

This study explores the impact of early motherhood on neonatal mortality, and how this differs between countries and regions. It assesses whether the risk of neonatal mortality is greater for younger adolescent mothers compared with mothers in later adolescence, and explores if differences reflect confounding socio-economic and health care utilisation factors. It also examines how the risks differ for first or subsequent pregnancies.

METHODS

The analysis uses 64 Demographic and Health Surveys collected between 2005 and 2015 from 45 countries to explore the relationship between adolescent motherhood (disaggregated as <16 years, 16/17 years and 18/19 years) and neonatal mortality. Both unadjusted bivariate association and logistic regression are used. Regional level multivariate models that adjust for a range of socio-economic, demographic and health service utilisation variables are estimated. Further stratified models are created to examine the excess risk for first and subsequent births separately.

FINDINGS

The risk of neonatal mortality in all regions was markedly greater for infants with mothers under 16 years old, although there was marked heterogeneity in patterns between regions. Adjusting for socio-economic, demographic and health service utilisation variables did not markedly change the odds ratios associated with age. The increased risks associated with adolescent motherhood are lowest for first births.

CONCLUSION

Our findings particularly highlight the importance of reducing adolescent births among the youngest age group as a strategy for addressing the problem of neonatal mortality, as well ensuring pregnant adolescents have access to quality maternal health services to protect the health of both themselves and their infants. The regional differences in increased risk are a novel finding which requires more exploration.

摘要

目的

本研究探讨了早期母亲身份对新生儿死亡率的影响,以及这种影响在不同国家和地区的差异。本研究评估了与青少年后期的母亲相比,年轻的青少年母亲的新生儿死亡率风险是否更高,并探讨了这种差异是否反映了混杂的社会经济和卫生保健利用因素。本研究还探讨了首次或随后妊娠的风险差异。

方法

本分析使用了 2005 年至 2015 年期间来自 45 个国家的 64 项人口与健康调查,探讨了青少年母亲身份(细分为<16 岁、16/17 岁和 18/19 岁)与新生儿死亡率之间的关系。使用未调整的双变量关联和逻辑回归进行分析。还估计了区域水平的多变量模型,这些模型调整了一系列社会经济、人口和卫生服务利用变量。进一步创建分层模型,分别检查首次和随后分娩的超额风险。

结果

所有地区的新生儿死亡率风险在母亲年龄<16 岁的婴儿中明显更高,尽管地区之间的模式存在明显的异质性。调整社会经济、人口和卫生服务利用变量并没有显著改变与年龄相关的优势比。青少年母亲身份相关的风险增加在首次分娩时最低。

结论

我们的研究结果特别强调了减少最年轻年龄组的青少年生育作为解决新生儿死亡率问题的策略的重要性,同时确保青少年孕妇能够获得优质的孕产妇保健服务,以保护她们自己和婴儿的健康。风险增加的区域差异是一个新的发现,需要进一步探讨。

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