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病理性近视眼光学相干断层扫描图像中双折射引起的巩膜伪影。

Birefringence-derived scleral artifacts in optical coherence tomography images of eyes with pathologic myopia.

机构信息

Department of Ophthalmology, Ibaraki Medical Center, Tokyo Medical University, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 300395, Japan.

Computational Optics Group, University of Tsukuba, Tsukuba, Japan.

出版信息

Sci Rep. 2022 Nov 16;12(1):19713. doi: 10.1038/s41598-022-23874-7.

DOI:10.1038/s41598-022-23874-7
PMID:36385309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9669004/
Abstract

We investigated birefringence-derived scleral artifacts in optical coherence tomography (OCT) images of eyes with pathologic myopia. This study included 76 eyes of 42 patients with pathologic myopia. Five sets of OCT B-scan images of the macula were obtained using commercial swept-source OCT. A dataset of prototype swept-source polarization-diversity OCT images was used to identify polarization-dependent OCT images (i.e., complex averaging of OCT signals from two polarization channels) and polarization-independent OCT images (i.e., intensity averaging of two OCT signals). Polarization-dependent OCT images and commercial OCT images were assessed for the presence of birefringence-derived artifacts by comparison with polarization-independent OCT images. Both polarization-dependent OCT images and commercial OCT images contained scleral vessel artifacts. Scleral vessel artifacts were present in 46 of 76 eyes (60.5%) imaged by polarization-dependent OCT and 17 of 76 eyes (22.4%) imaged by commercial OCT. The proportion of images that showed scleral vessel artifacts was significantly greater among polarization-dependent OCT images than among commercial OCT images (P < 0.001). Additionally, polarization-dependent OCT images showed low-intensity band artifacts. This study demonstrated the existence of birefringence-derived scleral artifacts in commercial OCT images and indicated that polarization-diversity OCT is an effective tool to evaluate the presence of these artifacts.

摘要

我们研究了病理性近视患者的光学相干断层扫描（OCT）图像中的双折射衍生的巩膜伪影。这项研究包括 42 名病理性近视患者的 76 只眼睛。使用商业扫频源 OCT 获得了 5 组黄斑 OCT B 扫描图像。使用原型扫频源偏振分集 OCT 图像数据集来识别偏振相关 OCT 图像（即来自两个偏振通道的 OCT 信号的复平均）和偏振无关 OCT 图像（即两个 OCT 信号的强度平均）。通过与偏振无关的 OCT 图像进行比较，评估偏振相关的 OCT 图像和商业 OCT 图像中是否存在双折射衍生的伪影。偏振相关的 OCT 图像和商业 OCT 图像都包含巩膜血管伪影。偏振相关 OCT 图像中，46 只眼（60.5%）存在巩膜血管伪影，商业 OCT 图像中，17 只眼（22.4%）存在巩膜血管伪影。偏振相关 OCT 图像中显示巩膜血管伪影的图像比例明显高于商业 OCT 图像（P<0.001）。此外，偏振相关 OCT 图像还显示出低强度带伪影。本研究证明了商业 OCT 图像中存在双折射衍生的巩膜伪影，并表明偏振分集 OCT 是评估这些伪影存在的有效工具。

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Transl Vis Sci Technol. 2021 Dec 1;10(14):29. doi: 10.1167/tvst.10.14.29.
2
En-face analysis of short posterior ciliary arteries crossing the sclera to choroid using wide-field swept-source optical coherence tomography.应用超广角扫频源光相干断层扫描对视神经周围巩膜至脉络膜短睫状后动脉进行面分析。
Sci Rep. 2021 Apr 22;11(1):8732. doi: 10.1038/s41598-021-88205-8.
3
Decreased choroidal and scleral thicknesses in highly myopic eyes with posterior staphyloma.
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Biomed Opt Express. 2024 Jan 31;15(2):1331-1354. doi: 10.1364/BOE.505395. eCollection 2024 Feb 1.
4
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4
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