Uchida A, Nade S, McCartney E, Ching W
J Orthop Res. 1985;3(1):65-77. doi: 10.1002/jor.1100030108.
Three different porous ceramics--calcium aluminate, calcium hydroxyapatite, and tricalcium phosphate--were implanted into the proximal tibia in rats and rabbits to study the interactions between these ceramics and a bony site that is abundant in bone marrow. New bone was consistently formed within the bone marrow surrounding and adjacent to all three types of ceramics. Calcium hydroxyapatite and tricalcium phosphate ceramics permitted bone ingrowth into their pores. The newly formed bone was found only in the part of the ceramic intruding into the bone, not in the portion protruding in the soft tissues outside the tibia. Partial replacement of the new bone opposite the medullary portion by new hemopoietic marrow occurred with longer implantation times. In contrast, no bone was seen within the pores of any of the calcium aluminate implants.
将三种不同的多孔陶瓷——铝酸钙、羟基磷灰石和磷酸三钙——植入大鼠和兔子的胫骨近端，以研究这些陶瓷与富含骨髓的骨部位之间的相互作用。在所有三种类型陶瓷周围和相邻的骨髓内均持续形成了新骨。羟基磷灰石和磷酸三钙陶瓷允许骨长入其孔隙。新形成的骨仅在陶瓷侵入骨的部分被发现，而不在胫骨外软组织中突出的部分。随着植入时间延长，与髓质部分相对的新骨部分被新的造血骨髓部分替代。相比之下，在任何铝酸钙植入物的孔隙内均未见到骨。
