Khatami Mehrdad, Mortazavi Seyed Mojtaba, Kishani-Farahani Zeinab, Amini Abbas, Amini Elham, Heli Hossein
School of Medicine, Bam University of Medical Sciences, Bam, Iran. 2.
Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 5.
Iran J Biotechnol. 2017 Aug 19;15(2):95-101. doi: 10.15171/ijb.1436. eCollection 2017.
Nanoparticles have been applied to medicine, hygiene, pharmacy and dentistry, and will bring significant advances in the prevention, diagnosis, drug delivery and treatment of disease. Green synthesis of metal nanoparticles has a very important role in nanobiotechnology, allowing production of non-toxic and eco-friendly particles. Green synthesis of silver nanoparticles (AgNPs) was studied using pine pollen as a novel, cost-effective, simple and non-hazardous bioresource. The antifungal activity of the synthesized AgNPs was investigated . Biosynthesis of AgNPs was conducted using pollen of pine (as a novel bioresource) acting as both reducing and capping agents. AgNPs were characterized using UV-visible spectroscopy, X-ray diffraction and transmission electron microscopy. In evaluation for antifungal properties, the synthesized AgNPs represented significant in vitro inhibitory effects on cultures. Pine pollen can mediate biosynthesis of colloidal AgNPs with an average size of 12 nm. AgNPs were formed at 22 °C and observed to be highly stable up to three months without precipitation or decreased antifungal property. AgNPs showed significant inhibitory effects against . The first report for a low-cost, simple, well feasible and eco-friendly procedure for biosynthesis of AgNPs was presented. The synthesized AgNPs by pine pollen were nontoxic and eco-friendly, and can be employed for large-scale production. The nanoparticles showed strong effect on quantitative inhibition and disruption of antifungal growth.
纳米颗粒已应用于医学、卫生、制药和牙科领域，并将在疾病的预防、诊断、药物递送和治疗方面带来重大进展。金属纳米颗粒的绿色合成在纳米生物技术中具有非常重要的作用，能够生产无毒且环保的颗粒。本研究以松花粉作为一种新型、经济高效、简便且无害的生物资源，对银纳米颗粒（AgNPs）的绿色合成进行了研究。对合成的AgNPs的抗真菌活性进行了研究。利用松花粉（作为一种新型生物资源）同时作为还原剂和封端剂进行AgNPs的生物合成。使用紫外可见光谱、X射线衍射和透射电子显微镜对AgNPs进行了表征。在抗真菌性能评估中，合成的AgNPs对培养物表现出显著的体外抑制作用。松花粉可以介导平均粒径为12 nm的胶体AgNPs的生物合成。AgNPs在22℃下形成，并且在长达三个月的时间内观察到高度稳定，没有沉淀或抗真菌性能下降。AgNPs对……表现出显著的抑制作用。本文首次报道了一种低成本、简便、可行且环保的AgNPs生物合成方法。松花粉合成的AgNPs无毒且环保，可用于大规模生产。这些纳米颗粒对真菌生长的定量抑制和破坏具有很强的作用。
