Japanese Herbal Kampo Hochu-Ekki-To or Juzen-Taiho-To after Surgery for Hip Fracture Does Not Reduce Infectious Complications.

BACKGROUND

Infectious complications after hip fracture surgery are common in the elderly. Although experimental studies have suggested that kampo medicine, Hochu-ekki-to and Juzen-taiho-to, can prevent infectious complications, only a few small clinical studies have been published to date.

PRIMARY STUDY OBJECTIVE

The aim of the present study is to investigate the impact of Hochu-ekki-to or Juzen-taiho-to on postoperative infectious complications in patients undergoing surgery for hip fracture.

METHODS AND DESIGN

In this retrospective cohort study using a nationwide inpatient database in Japan, we performed propensity score matching to compare patients who did or did not receive kampo medicine after surgery for hip fracture.

SETTINGS

A nationwide inpatient database.

PARTICIPANTS

Patients who did or did not receive kampo medicine after surgery for hip fracture.

INTERVENTION

Kampo medicine after surgery for hip fracture.

PRIMARY OUTCOME MEASURES

Infectious complications.

RESULTS

The proportions of postoperative infectious complications were not significantly different between the 424 propensity-matched pairs with and without kampo medicine (11 versus 8, = 0.644).

CONCLUSION

The present study suggests that Hochu-ekki-to or Juzen-taiho-to postoperatively is not associated with decreased occurrence of infectious complications in patients who underwent surgery for hip fracture.