Stull Carolyn, Valdes-Rodriguez Rodrigo, Shafer Brian M, Shevchenko Alina, Nattkemper Leigh A, Chan Yiong-Huak, Tabaac Sydney, Schardt Martin J, Najjar Dany M, Foster William J, Yosipovitch Gil
Departments of Dermatology.
Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.
Itch (Phila). 2017 Mar;2(1):e4. doi: 10.1097/itx.0000000000000004. Epub 2017 Mar 28.
In this cross-sectional study, we aimed to determine the prevalence and characteristics of chronic ocular itch in an outpatient ophthalmology and optometry clinic.
Four hundred patients from an outpatient ophthalmology and optometry clinic were enrolled. The presence and characteristics of chronic ocular itch were assessed by a questionnaire. Data regarding ophthalmologic, dermatologic, and systemic conditions as well as current medications were extracted from medical records.
Chronic ocular itch was present in 118 (29.5%) of 400 participants. Chronic ocular pruritus was significantly more prevalent in females [=0.015; odds ratio (OR)=1.8; 95% confidence interval (CI), 1.1-2.8] and was significantly associated with the presence of allergic conjunctivitis [51.8% (n=45); <0.001; OR=5.0; 95% CI, 3.0-8.3], dry eye syndrome [40.1% (75); <0.001; OR=2.6; 95% CI, 1.7-4.1], blepharitis [43.8% (n=21); =0.021; OR=2.0; 95% CI, 1.1-3.8], and atopic dermatitis [50.0% (n=10); =0.023; OR=2.6; 95% CI, 1.1-5.8]. Chronic ocular itch was not significantly associated with systemic conditions, or the use of prescribed ophthalmologic medications.
Chronic ocular itch is common and may be related to ophthalmologic or dermatologic pathologies. The present findings highlight the importance of identifying and managing this uncomfortable symptom that may negatively impact the quality of life and sleep of affected patients.
在这项横断面研究中，我们旨在确定门诊眼科和验光诊所中慢性眼部瘙痒的患病率及特征。
招募了来自门诊眼科和验光诊所的400名患者。通过问卷调查评估慢性眼部瘙痒的存在及特征。从病历中提取有关眼科、皮肤科和全身状况以及当前用药的数据。
400名参与者中有118名（29.5%）存在慢性眼部瘙痒。慢性眼部瘙痒在女性中更为普遍[=0.015；优势比（OR）=1.8；95%置信区间（CI），1.1 - 2.8]，并且与过敏性结膜炎[51.8%（n = 45）；<0.001；OR = 5.0；95% CI，3.0 - 8.3]、干眼综合征[40.1%（75）；<0.001；OR = 2.6；95% CI，1.7 - 4.1]、睑缘炎[43.8%（n = 21）；=0.021；OR = 2.0；95% CI，1.1 - 3.8]和特应性皮炎[50.0%（n = 10）；=0.023；OR = 2.6；95% CI，1.1 - 5.8]显著相关。慢性眼部瘙痒与全身状况或使用的处方眼科药物无显著关联。
慢性眼部瘙痒很常见，可能与眼科或皮肤科疾病有关。本研究结果凸显了识别和处理这种可能对受影响患者的生活质量和睡眠产生负面影响的不适症状的重要性。
