Ban Daisuke, Ogura Toshiro, Akahoshi Keiichi, Tanabe Minoru
Department of Hepatobiliary and Pancreatic Surgery Graduate School of Medicine Tokyo Medical and Dental University Tokyo Japan.
Ann Gastroenterol Surg. 2018 Feb 28;2(2):137-146. doi: 10.1002/ags3.12065. eCollection 2018 Mar.
Treatment strategy for hepatocellular carcinoma (HCC) requires optimal selection of therapies based on various factors related to tumor condition and liver functional reserve. Although several evidence-based guidelines have been proposed for the treatment of HCC, the criteria and range of indications differ among these guidelines according to the circumstances of each country. In European nations and the USA, patients with the Barcelona Clinic Liver Cancer stage 0-A are subjects for surgical resection, whereas in Asian countries, even those with the intermediate stage are regarded as surgical candidates. Furthermore, since the recent introduction and rapidly widely spreading use of laparoscopic liver resection, this technique has become an important treatment option for surgical resection. In this review article, we overview the current topics of treatment of HCC with a special focus on surgical therapy.
肝细胞癌（HCC）的治疗策略需要根据与肿瘤情况和肝功能储备相关的各种因素来优化治疗方案的选择。尽管已经提出了一些基于证据的HCC治疗指南，但这些指南的标准和适应证范围因每个国家的情况而异。在欧洲国家和美国，巴塞罗那临床肝癌分期0-A期的患者是手术切除的对象，而在亚洲国家，即使是中期患者也被视为手术候选者。此外，自从最近腹腔镜肝切除技术问世并迅速广泛应用以来，该技术已成为手术切除的重要治疗选择。在这篇综述文章中，我们概述了HCC治疗的当前热点，特别关注手术治疗。
