Loma Linda University, School of Public Health, Loma Linda, CA 92350, USA.
Politeknik Kesehatan Kemenkes Jakarta II, Jakarta 12120, Indonesia.
Nutrients. 2018 Jun 4;10(6):722. doi: 10.3390/nu10060722.
To investigate the association between plasma concentration of vitamin B and B intake from supplements, fortified foods, and animal source foods among vegetarians and non-vegetarians, we conducted a cross-sectional analysis among 728 participants of the Adventist Health Study 2 (AHS-2) calibration study. The median age of participants was 58 years, 65.4% were female, and 50.3% were White. We used six 24 h dietary recalls to measure B intake, serum vitamin B, and holotranscobalamin (holoTC) concentration. B supplements had a significantly positive association with plasma B among all subjects ( trend < 0.001), especially among vegans and lacto-ovo vegetarians ( trend < 0.001). Among non-users of B supplements, B intake from milk substitutes was significantly positively associated with holoTC ( trend < 0.004) and serum B12 ( trend < 0.030). In non-vegetarians, holoTC was significantly positively associated with B intake from eggs, while serum B was significantly positively associated with B intake from milk in the upper tertile compared to the lower, and B intake from meat in the middle compared to the lower tertile intake ( < 0.011). Supplements containing B followed by B intake from milk substitutes were significant contributors of plasma vitamin B concentration.
为了调查素食者和非素食者的血浆维生素 B 浓度与补充剂、强化食品和动物源食品中 B 摄入量之间的关系，我们对 Adventist Health Study 2（AHS-2）校准研究的 728 名参与者进行了横断面分析。参与者的中位年龄为 58 岁，65.4%为女性，50.3%为白人。我们使用了六次 24 小时膳食回忆来测量 B 摄入量、血清维生素 B 和全钴胺素（holoTC）浓度。B 补充剂与所有受试者的血浆 B 呈显著正相关（趋势<0.001），尤其是在纯素食者和乳蛋素食者中（趋势<0.001）。在不使用 B 补充剂的人群中，奶替代品中的 B 摄入量与 holoTC（趋势<0.004）和血清 B12（趋势<0.030）呈显著正相关。在非素食者中，holoTC 与鸡蛋中的 B 摄入量呈显著正相关，而血清 B 与上三分位的牛奶摄入量呈显著正相关，与中三分位的肉类摄入量呈显著正相关（<0.011）。含 B 的补充剂和随后的奶替代品中的 B 摄入量是血浆维生素 B 浓度的重要贡献者。
