Slowinska Katarzyna
Department of Chemistry and Biochemistry, California State University Long Beach, Long Beach, CA, USA.
Methods Mol Biol. 2018;1798:203-212. doi: 10.1007/978-1-4939-7893-9_16.
Cross-linking collagen results in the formation of a collagen matrix that is one of the most widely used biomaterials for applications in drug delivery, tissue engineering, molecular scaffolds, and materials for wound dressing. The properties of the collagen matrix depend on the cross-linking strategy employed. Here we describe the preparation and characterization of a nonfibrillar collagen matrix stabilized by cross-linking with tiopronin-protected, 3-4 nm polyvalent gold nanoparticles.
交联胶原蛋白会形成一种胶原蛋白基质，它是药物递送、组织工程、分子支架和伤口敷料材料等应用中使用最广泛的生物材料之一。胶原蛋白基质的性质取决于所采用的交联策略。在此，我们描述了一种通过与硫普罗宁保护的3-4纳米多价金纳米颗粒交联而稳定的非纤维状胶原蛋白基质的制备和表征。
