Department of Ophthalmology, The First Affiliated Hospital, China Medical University, Shenyang, China.
BMJ Open. 2013 Nov 19;3(11):e003787. doi: 10.1136/bmjopen-2013-003787.
Pterygium is considered to be a proliferative overgrowth of bulbar conjunctiva that can induce significant astigmatism and cause visual impairment; this is the first meta-analysis to investigate the pooled prevalence and risk factors for pterygium in the global world.
A systematic review and meta-analysis of population-based studies.
International.
A total of 20 studies with 900 545 samples were included.
The pooled prevalence and risk factors for pterygium.
20 studies were included. The pooled prevalence of pterygium was 10.2% (95% CI 6.3% to 16.1%). The pooled prevalence among men was higher than that among women (14.5% vs 13.6%). The proportion of participants with unilateral cases of pterygium was higher than that of participants with bilateral cases of pterygium. We found a trend that the higher pooled prevalence of pterygium was associated with decreasing geographical latitude and age in the world. The pooled OR was 2.32 (95% CI 1.66 to 3.23) for the male gender and 1.76 (95% CI 1.55 to 2.00) for outdoor activity, respectively.
The pooled prevalence of pterygium was relatively high, especially for low latitude regions and the elderly. There were many modifiable risk factors associated with pterygium to which healthcare providers should pay more attention.
翼状胬肉被认为是球结膜的过度增生，可引起明显的散光并导致视力损害；这是第一项调查全球翼状胬肉患病率和危险因素的荟萃分析。
基于人群的研究的系统评价和荟萃分析。
国际。
共纳入 20 项研究，涉及 900545 例样本。
翼状胬肉的患病率和危险因素的汇总。
纳入 20 项研究。翼状胬肉的总患病率为 10.2%（95%CI6.3%至 16.1%）。男性的患病率高于女性（14.5%比 13.6%）。单侧翼状胬肉患者的比例高于双侧翼状胬肉患者。我们发现一个趋势，即全球翼状胬肉的患病率随着地理纬度和年龄的降低而升高。总的来说，男性的合并 OR 为 2.32（95%CI1.66 至 3.23），户外活动的合并 OR 为 1.76（95%CI1.55 至 2.00）。
翼状胬肉的总患病率相对较高，尤其是在低纬度地区和老年人中。有许多与翼状胬肉相关的可改变的危险因素，医疗保健提供者应更加重视。
