College of Chemistry and Chemical engineering, Hunan University, Changsha, Hunan, 410082, China.
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, College of Materials and Chemical Engineering, Hainan University, Haikou, Hainan, 570228, China.
Chem Asian J. 2018 Sep 4;13(17):2277-2291. doi: 10.1002/asia.201800647. Epub 2018 Aug 1.
Three-component reactions can directly convert three reactants into the desired products in one pot and thus greatly shorten the synthetic path. Recently, transition-metal catalysis has been applied in the difunctionalization of alkenes and remarkable progress has been achieved to facilitate the construction of a wide range of functional molecules with high atom- and step-economic efficiency. This Focus Review highlights recent advances in this field.
三组分反应可以在一锅中将三种反应物直接转化为所需产物,从而大大缩短合成路径。最近,过渡金属催化已应用于烯烃的双官能团化反应,并取得了显著进展,从而促进了具有高原子经济性和步骤经济性的广泛功能分子的构建。本文重点介绍了该领域的最新进展。