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日本老年人群牙齿状况与合并症之间的相关性:一项横断面研究。

Correlation between dental conditions and comorbidities in an elderly Japanese population: A cross-sectional study.

作者信息

Ide Kazuki, Seto Kahori, Usui Tomoko, Tanaka Sachiko, Kawakami Koji

机构信息

Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health Center for the Promotion of Interdisciplinary Education and Research, Kyoto University, Kyoto Department of Medical Statistics, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, Japan.

出版信息

Medicine (Baltimore). 2018 Jun;97(24):e11075. doi: 10.1097/MD.0000000000011075.

Abstract

The purpose of this study was to investigate the correlation between dental conditions and comorbidities in an elderly population in Japan.A database constructed using data obtained from 12 nursing homes in Japan was used in this study. The study period ranged from January 2014 to December 2015, and elderly individuals with dental and other medical records were included in the analysis. Linear regression models were used to analyze univariate and multivariate correlation between dental conditions, comorbidities, and other sociodemographic/clinical backgrounds.After excluding individuals with missing data, 289 elderly individuals (107 men and 182 women; mean age, 85 years) were included in the analysis. These individuals had an average of 11.6 teeth, and the number decreased with older age (P < .001). The average number of decayed teeth was 1.4. A total of 116 subjects (40.1%) had dementia. In terms of comorbidities, dementia was not significantly associated with the number of present teeth (P = .56), but it was associated with the number of decayed teeth (P = .018). This association was also observed after adjusting for confounding variables in the multivariate regression analysis (P = .030).The number of decayed teeth was associated with dementia. While causality cannot be inferred from these observational results, the findings indicate that dental health could represent a marker of impending dementia, and probably represent a marker of general health status in the elderly population. Additional longitudinal studies are highly desirable to understand the causal relationships between dental conditions and comorbidities.

摘要

本研究旨在调查日本老年人群牙齿状况与合并症之间的相关性。本研究使用了一个基于从日本12家养老院获取的数据构建的数据库。研究期间为2014年1月至2015年12月,分析纳入了有牙齿和其他医疗记录的老年人。使用线性回归模型分析牙齿状况、合并症以及其他社会人口统计学/临床背景之间的单变量和多变量相关性。在排除数据缺失的个体后,289名老年人(107名男性和182名女性;平均年龄85岁)纳入分析。这些个体平均有11.6颗牙齿,且牙齿数量随年龄增长而减少(P<0.001)。龋齿的平均数量为1.4颗。共有116名受试者(40.1%)患有痴呆症。在合并症方面,痴呆症与现存牙齿数量无显著相关性(P=0.56),但与龋齿数量相关(P=0.018)。在多变量回归分析中对混杂变量进行调整后,这种关联依然存在(P=0.030)。龋齿数量与痴呆症相关。虽然无法从这些观察结果推断因果关系,但研究结果表明牙齿健康可能是即将发生痴呆症的一个标志,并且可能代表老年人群总体健康状况的一个标志。非常需要进一步的纵向研究来了解牙齿状况与合并症之间的因果关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e5/6023670/f775fdf62053/medi-97-e11075-g001.jpg

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