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镇痛技术的现状——犬猫急性疼痛管理药理学方法的最新进展。第1部分。

State of the art analgesia- recent developments in pharmacological approaches to acute pain management in dogs and cats. Part 1.

作者信息

Bradbrook C A, Clark L

机构信息

Ace Vets Ltd., Rossett, LL12 0BL, UK.

Davies Veterinary Specialists, Manor Farm Business Park, Higham Gobion, Herts, SG5 3HR, UK.

出版信息

Vet J. 2018 Aug;238:76-82. doi: 10.1016/j.tvjl.2018.06.003. Epub 2018 Jun 6.

Abstract

There has been considerable interest in acute pain management over recent years, focusing on pain assessment, pharmacological and non-pharmacological interventions. The evidence base for our clinical decision making and treatment of patients is increasing and becoming more robust. There is still a tendency to base some aspects of pain management on poor quality evidence and this requires further input in years to come. With new literature come new ideas and this review will detail the current knowledge base behind pharmacological management of acute pain in dogs and cats. The known mechanisms of action of each analgesic and its evidence will be considered. The first part of this review will consider the opioid and anti-inflammatory analgesics, describing their component drugs individually, thereby focusing on their mechanisms of action and the current evidence for their use in acute pain management.

摘要

近年来,人们对急性疼痛管理有着浓厚的兴趣,重点在于疼痛评估、药物和非药物干预。我们用于临床决策和治疗患者的证据基础正在不断增加且愈发坚实。然而,疼痛管理的某些方面仍倾向于基于质量欠佳的证据,这在未来几年需要进一步改进。随着新文献的出现,新的观点也随之而来,本综述将详细阐述犬猫急性疼痛药物管理背后的当前知识基础。将考虑每种镇痛药已知的作用机制及其证据。本综述的第一部分将探讨阿片类和抗炎镇痛药,分别描述其组成药物,从而聚焦于它们的作用机制以及目前用于急性疼痛管理的证据。

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