Davarpanah Mohammad Ali, Motazedian Nasrin, Jowkar Farideh
Shiraz HIV/AIDS Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
J Glob Infect Dis. 2018 Apr-Jun;10(2):80-83. doi: 10.4103/0974-777X.233000.
HIV infection remains as a major challenge facing medical sciences in the world today. Mucocutaneous manifestation was first observed in patients with HIV/AIDS in the early 1980s. The aim of this study was to identify various skin manifestations based on making careful clinical observations and performing the necessary tests.
A total of 240 patients whose disease was diagnosed using WB and ELISA tests, with dermatologic manifestations and were older than 18 years, participated in this study. These patients had referred to the voluntary counseling and testing center in Shiraz for routine examinations.
From the total of 240 participants, 158 were males (65.8%) and 82 were females (34.2%). The mean age was 40.87 ± 8.04 years. Dermatologic manifestations were of infectious origin in 79 (33%) of the participants. As the most common viral skin infections, herpes simplex was seen in 16 patients (6.7%), with herpes zoster ranking second with 15 patients (6.3%). No relationship was found between CD4 cell count and infectious or noninfectious dermatologic manifestations ( = 0.274).
No association was found between CD4 cell counts and dermatologic manifestations. Many skin disorders may appear in HIV/AIDS patients with normal CD4 cell counts.
艾滋病毒感染仍然是当今世界医学面临的一项重大挑战。20世纪80年代初,在艾滋病毒/艾滋病患者中首次观察到黏膜皮肤表现。本研究的目的是通过仔细的临床观察和进行必要的检测来识别各种皮肤表现。
共有240名患者参与了本研究,这些患者的疾病通过免疫印迹法(WB)和酶联免疫吸附测定(ELISA)检测确诊,有皮肤表现且年龄超过18岁。这些患者前往设拉子的自愿咨询和检测中心进行常规检查。
在总共240名参与者中,男性有158名(65.8%),女性有82名(34.2%)。平均年龄为40.87±8.04岁。79名(33%)参与者的皮肤表现源于感染。作为最常见的病毒性皮肤感染,16名患者(6.7%)出现单纯疱疹,带状疱疹以15名患者(6.3%)位居第二。未发现CD4细胞计数与感染性或非感染性皮肤表现之间存在关联(P = 0.274)。
未发现CD4细胞计数与皮肤表现之间存在关联。许多皮肤疾病可能出现在CD4细胞计数正常的艾滋病毒/艾滋病患者中。