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激光笔诱发的黄斑病变:表象之外另有隐情

Laser Pointer-Induced Maculopathy: More Than Meets the Eye.

作者信息

Mtanes Kamal, Mimouni Michael, Zayit-Soudry Shiri

出版信息

J Pediatr Ophthalmol Strabismus. 2018 Sep 20;55(5):312-318. doi: 10.3928/01913913-20180405-01. Epub 2018 Jun 19.

Abstract

PURPOSE

To describe the clinical findings in patients with laser-induced retinal injury.

METHODS

Consecutive patients presenting to a tertiary center between January 2014 and December 2015 following inadvertent ocular exposure to a laser pointer were included. Evaluation included a full ophthalmic examination and spectral-domain optical coherence tomography (SD-OCT).

RESULTS

Seven young patients (8 eyes) were identified. Their mean age was 18.7 years (median: 16 years; range: 12 to 36 years). In most cases, patients were exposed for several seconds to a 5-mW green laser. At presentation, all patients complained of a central/paracentral scotoma. Snellen best corrected visual acuity (BCVA) at presentation ranged from counting fingers to 6/6. In 5 eyes, a round, well-defined deep yellowish-orange discoloration at the level of the retinal pigment epithelium in the foveola, ranging from 150 to 350 μm in diameter, was noted on ophthalmoscopic examination. Additional findings were macular subhyaloid hemorrhage in 2 eyes and a full-thickness macular hole with cystoid macular edema in 1 eye. In all cases, baseline SD-OCT revealed disruption involving the photoreceptor inner segment/outer segment junction/ellipsoid zone band, and extended toward the inner aspect of the retinal pigment epithelium band, ranging from focal interruption to extensive full-thickness macular hole. All patients received oral corticosteroid treatment with prednisone (0.5 to 1 mg/kg). Follow-up ranged between 2 and 12 months. Over time, improvement in visual acuity to 6/8 and 6/6 was noted in all eyes but one, which remained poor at counting fingers from 2 meters. The visual improvement was associated with complete or near-complete restoration of the integrity of macular structure noted on SDOCT.

CONCLUSIONS

Commercial handheld laser pointers may inflict notable macular injury and damage vision permanently. Although good visual recovery was often noted, access to commercially available laser devices is potentially hazardous, especially to minors, and public awareness should be raised. [J Pediatr Ophthalmol Strabismus. 2018;55(5):312-318.].

摘要

目的

描述激光诱导的视网膜损伤患者的临床特征。

方法

纳入2014年1月至2015年12月间因意外眼部暴露于激光笔而就诊于三级中心的连续患者。评估包括全面的眼科检查和光谱域光学相干断层扫描(SD-OCT)。

结果

共识别出7例年轻患者(8只眼)。他们的平均年龄为18.7岁(中位数:16岁;范围:12至36岁)。在大多数情况下,患者暴露于5毫瓦的绿色激光数秒。就诊时,所有患者均主诉中心/旁中心暗点。就诊时Snellen最佳矫正视力(BCVA)范围从数指到6/6。眼科检查发现5只眼中,在黄斑中心凹视网膜色素上皮层水平有一个圆形、边界清晰的深黄橙色变色区,直径为150至350微米。其他发现包括2只眼有黄斑下玻璃体积血,1只眼有全层黄斑裂孔伴黄斑囊样水肿。在所有病例中,基线SD-OCT显示累及光感受器内节/外节连接/椭圆体带的破坏,并向视网膜色素上皮带的内侧延伸,范围从局灶性中断到广泛的全层黄斑裂孔。所有患者均接受泼尼松口服糖皮质激素治疗(0.5至1毫克/千克)。随访时间为2至12个月。随着时间的推移,除1只眼外,所有眼的视力均提高到6/8和6/6,该眼在2米处数指视力仍很差。视力改善与SD-OCT上黄斑结构完整性的完全或接近完全恢复有关。

结论

商用手持式激光笔可能会造成显著的黄斑损伤并永久性损害视力。尽管通常观察到良好的视力恢复,但接触商用激光设备存在潜在危险,尤其是对未成年人,应提高公众意识。[《小儿眼科与斜视杂志》。2018;55(5):312 - 318。]

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